Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations
Background: Polycystic ovary syndrome (PCOS) is a common, chronic gynaecological condition impacting women of reproductive age. Women with PCOS have hormonal, ovulatory, and metabolic dysfunction resulting in multiple symptoms. The correlation between hormonal disbalance and the impact on...
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Academia.edu Journals
2025-02-01
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| Online Access: | https://www.academia.edu/127497847/Systematic_review_and_meta_analysis_of_polycystic_ovary_syndrome_and_mental_health_among_Black_Asian_Minority_Ethnic_populations |
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| author | Gayathri Delanerolle Salma Ayis Vanya Barzilova Peter Phiri Priyanka Jagadeesan Yutain Zeng Sandali Ranaweera Ashish Shetty Nyla Haque Debasish Kar Kingshuk Majumder Shanaya Rathod Vanessa Raymont Jian Qing Shi Dharani K. Hapangama |
| author_facet | Gayathri Delanerolle Salma Ayis Vanya Barzilova Peter Phiri Priyanka Jagadeesan Yutain Zeng Sandali Ranaweera Ashish Shetty Nyla Haque Debasish Kar Kingshuk Majumder Shanaya Rathod Vanessa Raymont Jian Qing Shi Dharani K. Hapangama |
| author_sort | Gayathri Delanerolle |
| collection | DOAJ |
| description |
Background: Polycystic ovary syndrome (PCOS) is a common, chronic gynaecological condition impacting women of reproductive age. Women with PCOS have hormonal, ovulatory, and metabolic dysfunction resulting in multiple symptoms. The correlation between hormonal disbalance and the impact on women’s mental health (MH) has been researched for decades. However, the prevalence among different ethnicities has not been fully evaluated. Aim: The aim of this study was to explore the prevalence of PCOS among minority ethnic populations. Methods: A systematic methodology was developed, and a protocol was published in PROSPERO (CRD42020210863); moreover, a systematic review of publications between 1st January 1990 and 30th January 2021 was conducted. Multiple electronic databases were explored using keywords and MeSH terms. The finalised dataset was analysed using statistical methods such as random-effect models, subgroup analysis, and sensitivity analysis. These were used to determine the prevalence using variables of PND, anxiety, PTSD, and stress. Results: We included 30 studies reporting on 3,944 PCOS women. The majority of the included studies addressed depression, anxiety, and common mental health symptoms. Studies showed fair to poor methodological quality and included both observational studies and Randomised Clinical Trials (RCTs). Overall, 17% (95% CI: 7% to 29%) of the women with PCOS examined had a clinical diagnosis of major or severe depression; 33% (95% CI: 26% to 40%) had elevated depressive symptoms or a clinical diagnosis of depression; 41% (95% CI: 28% to 54%) reported anxiety symptoms; and 31% (95% CI: 15% to 51%) had a form of common mental health symptomatology or were taking psychiatric medication for anxiety and/or depression. The use of various tools to assess mental health symptoms was among the reasons for the substantial heterogeneity across studies. Conclusions: PCOS is associated with an increased risk of mental health disorders, including depression, anxiety, and other conditions. Approximately 30% of individuals with PCOS are taking psychiatric medication for anxiety and/or depression. While BAME populations account for about 20% of most of the samples studied, stratification by ethnicity was rarely attempted in study design makes it difficult to elucidate the MH impact of PCOS on different communities. |
| format | Article |
| id | doaj-art-6e79bb5e5e8242ab97a04035baed2772 |
| institution | OA Journals |
| issn | 2997-9196 |
| language | English |
| publishDate | 2025-02-01 |
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| spelling | doaj-art-6e79bb5e5e8242ab97a04035baed27722025-08-20T01:56:49ZengAcademia.edu JournalsAcademia Mental Health & Well-Being2997-91962025-02-012110.20935/MHealthWellB7404Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populationsGayathri Delanerolle0Salma Ayis1Vanya Barzilova2Peter Phiri3Priyanka Jagadeesan4Yutain Zeng5Sandali Ranaweera6Ashish Shetty7Nyla Haque8Debasish Kar9Kingshuk Majumder10Shanaya Rathod11Vanessa Raymont12Jian Qing Shi13Dharani K. Hapangama14Research & Innovation Department, Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Moorgreen Hospital, Botley Road, West End, Southampton SO30 3JB, United Kingdom.School of Population Health & Environmental Sciences, Kings College London, London SE1 1UL, United Kingdom.Department of Women's and Children's Health, University of Liverpool, Liverpool L69 3BX, United Kingdom.Research & Innovation Department, Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Moorgreen Hospital, Botley Road, West End, Southampton SO30 3JB, United Kingdom.Imperial College London, South Kensington, London SW7 2BX, United Kingdom.Department of Statistics and Data Science, Southern University of Science and Technology, Shenzen 518055, China.Research & Innovation Department, Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Moorgreen Hospital, Botley Road, West End, Southampton SO30 3JB, United Kingdom.University College London, London WC1E 6BT, United Kingdom.Department of Psychiatry, University of Oxford, Oxford OX1 3AZ, United Kingdom.Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford OX1 3AZ, United Kingdom.Gynaecology Department, Manchester University NHS Foundation Trust, Manchester M13 9WL, United Kingdom.Research & Innovation Department, Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Moorgreen Hospital, Botley Road, West End, Southampton SO30 3JB, United Kingdom.Department of Psychiatry, University of Oxford, Oxford OX1 3AZ, United Kingdom.Research & Innovation Department, Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Moorgreen Hospital, Botley Road, West End, Southampton SO30 3JB, United Kingdom.Department of Women's and Children's Health, University of Liverpool, Liverpool L69 3BX, United Kingdom. Background: Polycystic ovary syndrome (PCOS) is a common, chronic gynaecological condition impacting women of reproductive age. Women with PCOS have hormonal, ovulatory, and metabolic dysfunction resulting in multiple symptoms. The correlation between hormonal disbalance and the impact on women’s mental health (MH) has been researched for decades. However, the prevalence among different ethnicities has not been fully evaluated. Aim: The aim of this study was to explore the prevalence of PCOS among minority ethnic populations. Methods: A systematic methodology was developed, and a protocol was published in PROSPERO (CRD42020210863); moreover, a systematic review of publications between 1st January 1990 and 30th January 2021 was conducted. Multiple electronic databases were explored using keywords and MeSH terms. The finalised dataset was analysed using statistical methods such as random-effect models, subgroup analysis, and sensitivity analysis. These were used to determine the prevalence using variables of PND, anxiety, PTSD, and stress. Results: We included 30 studies reporting on 3,944 PCOS women. The majority of the included studies addressed depression, anxiety, and common mental health symptoms. Studies showed fair to poor methodological quality and included both observational studies and Randomised Clinical Trials (RCTs). Overall, 17% (95% CI: 7% to 29%) of the women with PCOS examined had a clinical diagnosis of major or severe depression; 33% (95% CI: 26% to 40%) had elevated depressive symptoms or a clinical diagnosis of depression; 41% (95% CI: 28% to 54%) reported anxiety symptoms; and 31% (95% CI: 15% to 51%) had a form of common mental health symptomatology or were taking psychiatric medication for anxiety and/or depression. The use of various tools to assess mental health symptoms was among the reasons for the substantial heterogeneity across studies. Conclusions: PCOS is associated with an increased risk of mental health disorders, including depression, anxiety, and other conditions. Approximately 30% of individuals with PCOS are taking psychiatric medication for anxiety and/or depression. While BAME populations account for about 20% of most of the samples studied, stratification by ethnicity was rarely attempted in study design makes it difficult to elucidate the MH impact of PCOS on different communities. https://www.academia.edu/127497847/Systematic_review_and_meta_analysis_of_polycystic_ovary_syndrome_and_mental_health_among_Black_Asian_Minority_Ethnic_populations |
| spellingShingle | Gayathri Delanerolle Salma Ayis Vanya Barzilova Peter Phiri Priyanka Jagadeesan Yutain Zeng Sandali Ranaweera Ashish Shetty Nyla Haque Debasish Kar Kingshuk Majumder Shanaya Rathod Vanessa Raymont Jian Qing Shi Dharani K. Hapangama Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations Academia Mental Health & Well-Being |
| title | Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations |
| title_full | Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations |
| title_fullStr | Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations |
| title_full_unstemmed | Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations |
| title_short | Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations |
| title_sort | systematic review and meta analysis of polycystic ovary syndrome and mental health among black asian minority ethnic populations |
| url | https://www.academia.edu/127497847/Systematic_review_and_meta_analysis_of_polycystic_ovary_syndrome_and_mental_health_among_Black_Asian_Minority_Ethnic_populations |
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