Solitary Colorectal Cancer Metastasis to the Pancreas
Introduction. Secondary pancreatic metastasis from other solid organ malignancy is rare and accounts for less than 2% of all pancreatic tumors. The aim of this study is to highlight that colorectal metastatic disease in the pancreas could be in selected cases an indication for surgery rather than fo...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2019/4891512 |
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| author | M. Karageorgou D. Myoteri T. Kotsis G. Polymeneas E. Bournakis D. Dellaportas |
| author_facet | M. Karageorgou D. Myoteri T. Kotsis G. Polymeneas E. Bournakis D. Dellaportas |
| author_sort | M. Karageorgou |
| collection | DOAJ |
| description | Introduction. Secondary pancreatic metastasis from other solid organ malignancy is rare and accounts for less than 2% of all pancreatic tumors. The aim of this study is to highlight that colorectal metastatic disease in the pancreas could be in selected cases an indication for surgery rather than for palliative chemotherapy. Case Presentation. We present a case of a 62-year-old Caucasian female with a history of rectal adenocarcinoma. Four years ago, the patient underwent low anterior resection of the rectosigmoid, post neoadjuvant chemoradiotherapy, with adjuvant chemotherapy. During her follow-up, imaging examinations revealed a lesion in the pancreatic neck with features indicating primary pancreatic cancer. Near-total distal pancreatectomy with en bloc splenectomy was performed. Histopathology revealed metastatic disease compatible with colorectal adenocarcinoma as the primary cancer. Second-line chemotherapy was decided from the institutional tumor board. The patient remains disease free one year later. Conclusion. Pancreatic lesions in patients with a history of extrapancreatic malignancy should raise suspicions of metastatic disease. Surgical intervention is a legitimate treatment option for these pancreatic lesions, since they represent solitary disease deposits and of course in the context of multidisciplinary meeting decisions, and after proper and extensive staging investigations. |
| format | Article |
| id | doaj-art-6e5d43929db34f53b9dd7bc2ec3741db |
| institution | OA Journals |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-6e5d43929db34f53b9dd7bc2ec3741db2025-08-20T02:06:30ZengWileyCase Reports in Surgery2090-69002090-69192019-01-01201910.1155/2019/48915124891512Solitary Colorectal Cancer Metastasis to the PancreasM. Karageorgou0D. Myoteri1T. Kotsis2G. Polymeneas3E. Bournakis4D. Dellaportas52nd Department of Surgery, Aretaieion University Hospital, Medical School of Athens, GreecePathology Department, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, GreeceVascular Surgery Unit, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Greece2nd Department of Surgery, Aretaieion University Hospital, Medical School of Athens, GreeceOncology Unit, 2nd Department of Surgery, Aretaieio Hospital, Medical School, National and Kapodistrian University of Athens, V. Sophias 76, 11528 Athens, Greece2nd Department of Surgery, Aretaieion University Hospital, Medical School of Athens, GreeceIntroduction. Secondary pancreatic metastasis from other solid organ malignancy is rare and accounts for less than 2% of all pancreatic tumors. The aim of this study is to highlight that colorectal metastatic disease in the pancreas could be in selected cases an indication for surgery rather than for palliative chemotherapy. Case Presentation. We present a case of a 62-year-old Caucasian female with a history of rectal adenocarcinoma. Four years ago, the patient underwent low anterior resection of the rectosigmoid, post neoadjuvant chemoradiotherapy, with adjuvant chemotherapy. During her follow-up, imaging examinations revealed a lesion in the pancreatic neck with features indicating primary pancreatic cancer. Near-total distal pancreatectomy with en bloc splenectomy was performed. Histopathology revealed metastatic disease compatible with colorectal adenocarcinoma as the primary cancer. Second-line chemotherapy was decided from the institutional tumor board. The patient remains disease free one year later. Conclusion. Pancreatic lesions in patients with a history of extrapancreatic malignancy should raise suspicions of metastatic disease. Surgical intervention is a legitimate treatment option for these pancreatic lesions, since they represent solitary disease deposits and of course in the context of multidisciplinary meeting decisions, and after proper and extensive staging investigations.http://dx.doi.org/10.1155/2019/4891512 |
| spellingShingle | M. Karageorgou D. Myoteri T. Kotsis G. Polymeneas E. Bournakis D. Dellaportas Solitary Colorectal Cancer Metastasis to the Pancreas Case Reports in Surgery |
| title | Solitary Colorectal Cancer Metastasis to the Pancreas |
| title_full | Solitary Colorectal Cancer Metastasis to the Pancreas |
| title_fullStr | Solitary Colorectal Cancer Metastasis to the Pancreas |
| title_full_unstemmed | Solitary Colorectal Cancer Metastasis to the Pancreas |
| title_short | Solitary Colorectal Cancer Metastasis to the Pancreas |
| title_sort | solitary colorectal cancer metastasis to the pancreas |
| url | http://dx.doi.org/10.1155/2019/4891512 |
| work_keys_str_mv | AT mkarageorgou solitarycolorectalcancermetastasistothepancreas AT dmyoteri solitarycolorectalcancermetastasistothepancreas AT tkotsis solitarycolorectalcancermetastasistothepancreas AT gpolymeneas solitarycolorectalcancermetastasistothepancreas AT ebournakis solitarycolorectalcancermetastasistothepancreas AT ddellaportas solitarycolorectalcancermetastasistothepancreas |