Prioritization of causal genes from genome-wide association studies by Bayesian data integration across loci.

Prioritization of causal genes from genome-wide association studies by Bayesian data integration across loci.

<h4>Motivation</h4>Genome-wide association studies (GWAS) have identified genetic variants, usually single-nucleotide polymorphisms (SNPs), associated with human traits, including disease and disease risk. These variants (or causal variants in linkage disequilibrium with them) usually af...

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Bibliographic Details
Main Authors: Zeinab Mousavi, Marios Arvanitis, ThuyVy Duong, Jennifer A Brody, Alexis Battle, Nona Sotoodehnia, Ali Shojaie, Dan E Arking, Joel S Bader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012725
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