Immunoinformatics based designing of a multi-epitope cancer vaccine targeting programmed cell death ligand 1

Immunoinformatics based designing of a multi-epitope cancer vaccine targeting programmed cell death ligand 1

Abstract Tumor cells express programmed cell death ligand 1 (PD-L1), which recognizes the immune checkpoint molecule programmed cell death 1 (PD-1) on T cells, suppressing the antitumor immune response. Inhibiting the PD-1:PD-L1 interaction has the potential to reactivate the immune response against...

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Bibliographic Details
Main Authors: Syed Sahajada Mahafujul Alam, Showkat Ahmad Mir, Arijit Samanta, Binata Nayak, Safdar Ali, Mehboob Hoque
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Cancer immunotherapy
Cancer vaccine
Immunoinformatics
Multi-epitope vaccine
PD-L1
Online Access:https://doi.org/10.1038/s41598-025-87063-y
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https://doi.org/10.1038/s41598-025-87063-y

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