Effect of hysteroscopic examination on the outcome of in vitro fertilization
Bacground/Aim. Implantation failure after embryo transfer is one of the main problems of in vitro fartilization (IVF) and intrauterine pathologies can lead to unsuccessful outcome. The aim of this study was to determine if hysteroscopic examination of uterine cavity and consequent treatment of i...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2011-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501106476T.pdf |
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| author | Trninić-Pjević Aleksandra Kopitović Vesna Pop-Trajković Sonja Bjelica Artur Bujas Irena Tabš Dunja Ilić Đorđe Stajić Dragan |
| author_facet | Trninić-Pjević Aleksandra Kopitović Vesna Pop-Trajković Sonja Bjelica Artur Bujas Irena Tabš Dunja Ilić Đorđe Stajić Dragan |
| author_sort | Trninić-Pjević Aleksandra |
| collection | DOAJ |
| description | Bacground/Aim. Implantation failure after embryo transfer is one of the main problems of in vitro fartilization (IVF) and intrauterine pathologies can lead to unsuccessful outcome. The aim of this study was to determine if hysteroscopic examination of uterine cavity and consequent treatment of intrauterine lesions prior to IVF could improve the pregnancy rate in women under 38. Methods. This study included 480 patients under 38, who had undergone IVF or IVFICSI - embryo transfer cycles, in which one or more good quality embryos were transferred. By transvaginal sonography performed within the past 2 months, the uterus was found normal in all the patients enrolled in our IVF unit. The patients were divided into three groups: group A - with no hysteroscopic evaluation and no pathology, group B - with hysteroscopy but no pathology, and group C - with abnormal hysteroscopy finding and corresponding treatment. Results. The obtained results revaled no difference in the mean age, duration of infertility, number of mature oocytes in either group (p > 0.05). Clinical pregnancy rates in the groups A, B and C were 36.9%, 58.75% and 32.7%, respectively, and delivery rates were 27.5%, 48.7% and 25.7%, respectively. There was a statistically significant difference among the groups concerning pregnancy and delivery rates. Conclusion. Considering the results of this study we could conclude that hysteroscopy, as a routine examination, should be performed before the first IVF-ET cycle in all patients thereby reducing the failures and then the costs of IVF-ET. |
| format | Article |
| id | doaj-art-6e4cff49ba894e14b39277a4e528409e |
| institution | Kabale University |
| issn | 0042-8450 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-6e4cff49ba894e14b39277a4e528409e2025-08-20T03:33:56ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502011-01-0168647648010.2298/VSP1106476TEffect of hysteroscopic examination on the outcome of in vitro fertilizationTrninić-Pjević AleksandraKopitović VesnaPop-Trajković SonjaBjelica ArturBujas IrenaTabš DunjaIlić ĐorđeStajić DraganBacground/Aim. Implantation failure after embryo transfer is one of the main problems of in vitro fartilization (IVF) and intrauterine pathologies can lead to unsuccessful outcome. The aim of this study was to determine if hysteroscopic examination of uterine cavity and consequent treatment of intrauterine lesions prior to IVF could improve the pregnancy rate in women under 38. Methods. This study included 480 patients under 38, who had undergone IVF or IVFICSI - embryo transfer cycles, in which one or more good quality embryos were transferred. By transvaginal sonography performed within the past 2 months, the uterus was found normal in all the patients enrolled in our IVF unit. The patients were divided into three groups: group A - with no hysteroscopic evaluation and no pathology, group B - with hysteroscopy but no pathology, and group C - with abnormal hysteroscopy finding and corresponding treatment. Results. The obtained results revaled no difference in the mean age, duration of infertility, number of mature oocytes in either group (p > 0.05). Clinical pregnancy rates in the groups A, B and C were 36.9%, 58.75% and 32.7%, respectively, and delivery rates were 27.5%, 48.7% and 25.7%, respectively. There was a statistically significant difference among the groups concerning pregnancy and delivery rates. Conclusion. Considering the results of this study we could conclude that hysteroscopy, as a routine examination, should be performed before the first IVF-ET cycle in all patients thereby reducing the failures and then the costs of IVF-ET.http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501106476T.pdffertilization in vitrohysteroscopyuterine diseasespregnancy outcomesensitivity and specificity |
| spellingShingle | Trninić-Pjević Aleksandra Kopitović Vesna Pop-Trajković Sonja Bjelica Artur Bujas Irena Tabš Dunja Ilić Đorđe Stajić Dragan Effect of hysteroscopic examination on the outcome of in vitro fertilization Vojnosanitetski Pregled fertilization in vitro hysteroscopy uterine diseases pregnancy outcome sensitivity and specificity |
| title | Effect of hysteroscopic examination on the outcome of in vitro fertilization |
| title_full | Effect of hysteroscopic examination on the outcome of in vitro fertilization |
| title_fullStr | Effect of hysteroscopic examination on the outcome of in vitro fertilization |
| title_full_unstemmed | Effect of hysteroscopic examination on the outcome of in vitro fertilization |
| title_short | Effect of hysteroscopic examination on the outcome of in vitro fertilization |
| title_sort | effect of hysteroscopic examination on the outcome of in vitro fertilization |
| topic | fertilization in vitro hysteroscopy uterine diseases pregnancy outcome sensitivity and specificity |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501106476T.pdf |
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