Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people

According to epidemiological studies, in Russia there is a tendency towards an increase in sudden cardiac death (SCD), including among young workingage people. The leading mechanism for SCD in young patients, including those with undifferentiated connective tissue disease, is recognized as rhythm an...

Full description

Saved in:
Bibliographic Details
Main Authors: E. N Loginova, E. A Kirh, G. I Nechaeva, A. I Martynov, I. V Druk, A. A Semenkin, A. N Dakuko
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2022-11-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/4991
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850030922171154432
author E. N Loginova
E. A Kirh
G. I Nechaeva
A. I Martynov
I. V Druk
A. A Semenkin
A. N Dakuko
author_facet E. N Loginova
E. A Kirh
G. I Nechaeva
A. I Martynov
I. V Druk
A. A Semenkin
A. N Dakuko
author_sort E. N Loginova
collection DOAJ
description According to epidemiological studies, in Russia there is a tendency towards an increase in sudden cardiac death (SCD), including among young workingage people. The leading mechanism for SCD in young patients, including those with undifferentiated connective tissue disease, is recognized as rhythm and conduction disorders. At the same time, the most tragic cases are the first and only manifestation of SCD in children and young people without structural heart disease. The article presents a brief analysis of the genetic causes of life-threatening rhythm and conduction disorders in young people, as well as a generalization of the modern possibilities of a personalized diagnostic approach from the standpoint of early cardiovascular prevention. Timely genetic diagnosis of SCD risk makes it possible to identify a predisposition to the development of a fatal event long before its occurrence, which contributes to the timely implementation of preventive measures within a high cardiovascular risk strategy and secondary prevention, maintaining working capacity, creative and social activity of young patients, and improving the quality of life.
format Article
id doaj-art-6e2509caa02e417fb21deecccbc60f01
institution DOAJ
issn 1560-4071
2618-7620
language Russian
publishDate 2022-11-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-6e2509caa02e417fb21deecccbc60f012025-08-20T02:59:06Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-11-01271010.15829/1560-4071-2022-49913589Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young peopleE. N Loginova0E. A Kirh1G. I Nechaeva2A. I Martynov3I. V Druk4A. A Semenkin5A. N Dakuko6Omsk State Medical UniversityOmsk State Medical UniversityOmsk State Medical UniversityA.I. Yevdokimov Moscow State University of Medicine and DentistryOmsk State Medical UniversityOmsk State Medical UniversityOmsk State Medical UniversityAccording to epidemiological studies, in Russia there is a tendency towards an increase in sudden cardiac death (SCD), including among young workingage people. The leading mechanism for SCD in young patients, including those with undifferentiated connective tissue disease, is recognized as rhythm and conduction disorders. At the same time, the most tragic cases are the first and only manifestation of SCD in children and young people without structural heart disease. The article presents a brief analysis of the genetic causes of life-threatening rhythm and conduction disorders in young people, as well as a generalization of the modern possibilities of a personalized diagnostic approach from the standpoint of early cardiovascular prevention. Timely genetic diagnosis of SCD risk makes it possible to identify a predisposition to the development of a fatal event long before its occurrence, which contributes to the timely implementation of preventive measures within a high cardiovascular risk strategy and secondary prevention, maintaining working capacity, creative and social activity of young patients, and improving the quality of life.https://russjcardiol.elpub.ru/jour/article/view/4991sudden cardiac deatharrhythmiasgenetic diagnosis
spellingShingle E. N Loginova
E. A Kirh
G. I Nechaeva
A. I Martynov
I. V Druk
A. A Semenkin
A. N Dakuko
Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people
Российский кардиологический журнал
sudden cardiac death
arrhythmias
genetic diagnosis
title Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people
title_full Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people
title_fullStr Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people
title_full_unstemmed Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people
title_short Role of genetic research in the prevention of life-threatening rhythm and cardiac conduction disorders in young people
title_sort role of genetic research in the prevention of life threatening rhythm and cardiac conduction disorders in young people
topic sudden cardiac death
arrhythmias
genetic diagnosis
url https://russjcardiol.elpub.ru/jour/article/view/4991
work_keys_str_mv AT enloginova roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople
AT eakirh roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople
AT ginechaeva roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople
AT aimartynov roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople
AT ivdruk roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople
AT aasemenkin roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople
AT andakuko roleofgeneticresearchinthepreventionoflifethreateningrhythmandcardiacconductiondisordersinyoungpeople