S-Gal™: An Autoclavable Dye for Color Selection of Cloned DNA Inserts

Blue/white selection is the standard method for detecting a cloned DNA fragment. In the absence of an insert, uninterrupted expression of the vector-encodeda-complement of β-galactosidase (β-gal), results in the hydrolysis of X-gal (5-bromo-4-chloro-3-indolyl β-d-galactoside) and the subsequent blue...

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Bibliographic Details
Main Authors: Ken Heuermann, Jennifer Cosgrove
Format: Article
Language:English
Published: Taylor & Francis Group 2001-05-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/01305pf01
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