Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification
The diagnosis, interpretation, and classification of melanocytic tumors is a very complex topic in the pathology and dermatopathology field that lacks standardization and is still subject to discordance and debate. Here, we review the definitions of dysplastic nevus and superficial atypical melanocy...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Dermatopathology |
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| Online Access: | https://www.mdpi.com/2296-3529/12/1/3 |
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| author | Sébastien Menzinger Rastine Merat Gürkan Kaya |
| author_facet | Sébastien Menzinger Rastine Merat Gürkan Kaya |
| author_sort | Sébastien Menzinger |
| collection | DOAJ |
| description | The diagnosis, interpretation, and classification of melanocytic tumors is a very complex topic in the pathology and dermatopathology field that lacks standardization and is still subject to discordance and debate. Here, we review the definitions of dysplastic nevus and superficial atypical melanocytic proliferations and provide an overview of some areas still subject to debate and some attempts of standardization. Furthermore, we describe an algorithmic classification, and provide some examples of clinico-pathological correlation. This step-by-step algorithm has an educational purpose and may automatize the work of dermatopathologists. We hope that through further molecular studies, this fine-grained scheme will prove to be related to the biological behavior of these atypical melanocytic lesions. |
| format | Article |
| id | doaj-art-6dff2396ccb54f2b8fbf7ccf54c499e9 |
| institution | DOAJ |
| issn | 2296-3529 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dermatopathology |
| spelling | doaj-art-6dff2396ccb54f2b8fbf7ccf54c499e92025-08-20T02:42:40ZengMDPI AGDermatopathology2296-35292025-01-01121310.3390/dermatopathology12010003Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological ClassificationSébastien Menzinger0Rastine Merat1Gürkan Kaya2Department of Dermatology and Venereology, University Hospital of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205 Genève, SwitzerlandDepartment of Dermatology and Venereology, University Hospital of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205 Genève, SwitzerlandDepartment of Dermatology and Venereology, University Hospital of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205 Genève, SwitzerlandThe diagnosis, interpretation, and classification of melanocytic tumors is a very complex topic in the pathology and dermatopathology field that lacks standardization and is still subject to discordance and debate. Here, we review the definitions of dysplastic nevus and superficial atypical melanocytic proliferations and provide an overview of some areas still subject to debate and some attempts of standardization. Furthermore, we describe an algorithmic classification, and provide some examples of clinico-pathological correlation. This step-by-step algorithm has an educational purpose and may automatize the work of dermatopathologists. We hope that through further molecular studies, this fine-grained scheme will prove to be related to the biological behavior of these atypical melanocytic lesions.https://www.mdpi.com/2296-3529/12/1/3dysplastic nevussuperficial borderline atypical melanocytic lesionmelanomadermatoscopyclinico-pathological correlationclassification |
| spellingShingle | Sébastien Menzinger Rastine Merat Gürkan Kaya Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification Dermatopathology dysplastic nevus superficial borderline atypical melanocytic lesion melanoma dermatoscopy clinico-pathological correlation classification |
| title | Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification |
| title_full | Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification |
| title_fullStr | Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification |
| title_full_unstemmed | Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification |
| title_short | Dysplastic Nevi and Superficial Borderline Atypical Melanocytic Lesions: Description of an Algorithmic Clinico-Pathological Classification |
| title_sort | dysplastic nevi and superficial borderline atypical melanocytic lesions description of an algorithmic clinico pathological classification |
| topic | dysplastic nevus superficial borderline atypical melanocytic lesion melanoma dermatoscopy clinico-pathological correlation classification |
| url | https://www.mdpi.com/2296-3529/12/1/3 |
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