A complex clinical case of intracardiac leiomyomatosis
Abstract Background Intracardiac leiomyomatosis (ICL) is an uncommon condition characterized by the proliferation of intravascular tissue within the veins, leading to the development of tumor emboli. This can pose a significant threat to life when the tumor invades cardiac structures. The diagnostic...
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| Language: | English |
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BMC
2025-02-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-025-04561-7 |
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| author | Yuanzhi Li Yidan Li Min Liang Lanlan Sun Weiwei Zhu Liqun Wei Xueyan Ding Dichen Guo Xiuzhang Lv |
| author_facet | Yuanzhi Li Yidan Li Min Liang Lanlan Sun Weiwei Zhu Liqun Wei Xueyan Ding Dichen Guo Xiuzhang Lv |
| author_sort | Yuanzhi Li |
| collection | DOAJ |
| description | Abstract Background Intracardiac leiomyomatosis (ICL) is an uncommon condition characterized by the proliferation of intravascular tissue within the veins, leading to the development of tumor emboli. This can pose a significant threat to life when the tumor invades cardiac structures. The diagnostic process for this condition is complex and presents considerable challenges. Case presentation We report a case of a 38-year-old female patient whose pulmonary artery computed tomography (CT) revealed low density structure in the branches of the pulmonary artery. Echocardiography revealed a mobile tumor within the right heart chambers and pulmonary trunks as well as characteristic thickening of the ventricular septum consistent with hypertrophic cardiomyopathy (HCM). Magnetic resonance imaging (MRI) revealed a mass in the right anterior uterine wall, extending to the inferior vena cava (IVC) and right iliac vein. Post-surgery histopathological analysis confirmed a diagnosis of intravenous leiomyomatosis (IVL). Conclusions When IVL affects the heart, echocardiography is the best diagnostic tool for detecting the disease. CT and MRI are essential in identifying the location and extent of the tumor, as well as in evaluating prognosis. |
| format | Article |
| id | doaj-art-6dfdbd472bd645cebb7a557cf7634eea |
| institution | DOAJ |
| issn | 1471-2261 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-6dfdbd472bd645cebb7a557cf7634eea2025-08-20T03:10:57ZengBMCBMC Cardiovascular Disorders1471-22612025-02-012511510.1186/s12872-025-04561-7A complex clinical case of intracardiac leiomyomatosisYuanzhi Li0Yidan Li1Min Liang2Lanlan Sun3Weiwei Zhu4Liqun Wei5Xueyan Ding6Dichen Guo7Xiuzhang Lv8Department of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Radiology, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityDepartment of Ultrasound, Beijing Chao Yang Hospital, Capital Medical UniversityAbstract Background Intracardiac leiomyomatosis (ICL) is an uncommon condition characterized by the proliferation of intravascular tissue within the veins, leading to the development of tumor emboli. This can pose a significant threat to life when the tumor invades cardiac structures. The diagnostic process for this condition is complex and presents considerable challenges. Case presentation We report a case of a 38-year-old female patient whose pulmonary artery computed tomography (CT) revealed low density structure in the branches of the pulmonary artery. Echocardiography revealed a mobile tumor within the right heart chambers and pulmonary trunks as well as characteristic thickening of the ventricular septum consistent with hypertrophic cardiomyopathy (HCM). Magnetic resonance imaging (MRI) revealed a mass in the right anterior uterine wall, extending to the inferior vena cava (IVC) and right iliac vein. Post-surgery histopathological analysis confirmed a diagnosis of intravenous leiomyomatosis (IVL). Conclusions When IVL affects the heart, echocardiography is the best diagnostic tool for detecting the disease. CT and MRI are essential in identifying the location and extent of the tumor, as well as in evaluating prognosis.https://doi.org/10.1186/s12872-025-04561-7Intracardiac leiomyomatosisEchocardiographyHypertrophic cardiomyopathy |
| spellingShingle | Yuanzhi Li Yidan Li Min Liang Lanlan Sun Weiwei Zhu Liqun Wei Xueyan Ding Dichen Guo Xiuzhang Lv A complex clinical case of intracardiac leiomyomatosis BMC Cardiovascular Disorders Intracardiac leiomyomatosis Echocardiography Hypertrophic cardiomyopathy |
| title | A complex clinical case of intracardiac leiomyomatosis |
| title_full | A complex clinical case of intracardiac leiomyomatosis |
| title_fullStr | A complex clinical case of intracardiac leiomyomatosis |
| title_full_unstemmed | A complex clinical case of intracardiac leiomyomatosis |
| title_short | A complex clinical case of intracardiac leiomyomatosis |
| title_sort | complex clinical case of intracardiac leiomyomatosis |
| topic | Intracardiac leiomyomatosis Echocardiography Hypertrophic cardiomyopathy |
| url | https://doi.org/10.1186/s12872-025-04561-7 |
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