Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022

Abstract Background Nontyphoidal Salmonella (NTS) is the most commonly reported foodborne gastrointestinal infection and ranks among the top three causes of foodborne bacterial outbreaks in China. Methods This study analyzed NTS data from the Foodborne Disease Surveillance System in China from 2013...

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Main Authors: Tongyu Wang, Weiwei Li, Ronghua Zhang, Jian Wen, Shuang Liu, Yuyan Jiang, Li Lin, Weiwei Chen, Jinjun Liang, Xiaochen Ma, Yijing Zhou, Haihong Han, Jikai Liu, Penghui Fan, Yunchang Guo, Linlin Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-23439-z
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author Tongyu Wang
Weiwei Li
Ronghua Zhang
Jian Wen
Shuang Liu
Yuyan Jiang
Li Lin
Weiwei Chen
Jinjun Liang
Xiaochen Ma
Yijing Zhou
Haihong Han
Jikai Liu
Penghui Fan
Yunchang Guo
Linlin Wang
author_facet Tongyu Wang
Weiwei Li
Ronghua Zhang
Jian Wen
Shuang Liu
Yuyan Jiang
Li Lin
Weiwei Chen
Jinjun Liang
Xiaochen Ma
Yijing Zhou
Haihong Han
Jikai Liu
Penghui Fan
Yunchang Guo
Linlin Wang
author_sort Tongyu Wang
collection DOAJ
description Abstract Background Nontyphoidal Salmonella (NTS) is the most commonly reported foodborne gastrointestinal infection and ranks among the top three causes of foodborne bacterial outbreaks in China. Methods This study analyzed NTS data from the Foodborne Disease Surveillance System in China from 2013 to 2022 to summarize epidemiological features and assess reporting rate changes. We employed joinpoint regression model to calculate the annual percentage change in NTS reporting rate, sex reporting rate, as well as rural-urban reporting rate. We applied the Pearson correlation coefficient to evaluate the correlation of NTS reporting rate and the national per capita consumption of major foods and cases of COVID-19. Results During this period, 55,266 NTS cases were reported, with reporting rates increasing significantly (AAPC [CRR] = 21.89%). Urban areas accounted for 70.06% of cases, but rural patients had higher hospitalization rates than urban ones (41.54% vs. 33.69%, p < 0.001). Children aged 0–4 years constituted 53.59% of cases and showed higher hospitalization rates (p < 0.05). Salmonella Typhimurium (31.07%) and Enteritidis (15.89%) were the leading serotypes. NTS reporting rates were strongly correlated with national per-capita consumption of fruit (r = 0.98), poultry (r = 0.95), aquatic products (r = 0.95), eggs (r = 0.94), vegetables (r = 0.79), dairy (r = 0.73), and meat (r = 0.65). Conclusion This study highlights the growing public health burden of Salmonella infection in China, with a sharp rise in reporting rates and major rural-urban differences. Over half of the cases involved children under 5 years old, underscoring the urgent need to enhance food safety measures, particularly for vulnerable populations.
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spelling doaj-art-6df5943c0d094e76baf74417709482c02025-08-20T03:04:21ZengBMCBMC Public Health1471-24582025-07-0125111110.1186/s12889-025-23439-zEpidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022Tongyu Wang0Weiwei Li1Ronghua Zhang2Jian Wen3Shuang Liu4Yuyan Jiang5Li Lin6Weiwei Chen7Jinjun Liang8Xiaochen Ma9Yijing Zhou10Haihong Han11Jikai Liu12Penghui Fan13Yunchang Guo14Linlin Wang15Department of Epidemiology and Biostatistics, School of Public Health, Peking UniversityNHC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk AssessmentZhejiang Provincial Center for Disease Control and PreventionGuangdong Provincial Center for Disease Control and PreventionHubei Provincial Center for Disease Control and PreventionGuangxi Zhuang Autonomous Region Center for Disease Control and PreventionSichuan Center for Disease Control and PreventionFujian Center for Disease Control and PreventionHunan Provincial Center for Disease Control and PreventionBeijing Center for Disease Prevention and ControlJiangsu Provincial Center for Disease Control and PreventionNHC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk AssessmentNHC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk AssessmentNHC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk AssessmentNHC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk AssessmentInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking UniversityAbstract Background Nontyphoidal Salmonella (NTS) is the most commonly reported foodborne gastrointestinal infection and ranks among the top three causes of foodborne bacterial outbreaks in China. Methods This study analyzed NTS data from the Foodborne Disease Surveillance System in China from 2013 to 2022 to summarize epidemiological features and assess reporting rate changes. We employed joinpoint regression model to calculate the annual percentage change in NTS reporting rate, sex reporting rate, as well as rural-urban reporting rate. We applied the Pearson correlation coefficient to evaluate the correlation of NTS reporting rate and the national per capita consumption of major foods and cases of COVID-19. Results During this period, 55,266 NTS cases were reported, with reporting rates increasing significantly (AAPC [CRR] = 21.89%). Urban areas accounted for 70.06% of cases, but rural patients had higher hospitalization rates than urban ones (41.54% vs. 33.69%, p < 0.001). Children aged 0–4 years constituted 53.59% of cases and showed higher hospitalization rates (p < 0.05). Salmonella Typhimurium (31.07%) and Enteritidis (15.89%) were the leading serotypes. NTS reporting rates were strongly correlated with national per-capita consumption of fruit (r = 0.98), poultry (r = 0.95), aquatic products (r = 0.95), eggs (r = 0.94), vegetables (r = 0.79), dairy (r = 0.73), and meat (r = 0.65). Conclusion This study highlights the growing public health burden of Salmonella infection in China, with a sharp rise in reporting rates and major rural-urban differences. Over half of the cases involved children under 5 years old, underscoring the urgent need to enhance food safety measures, particularly for vulnerable populations.https://doi.org/10.1186/s12889-025-23439-zNontyphoidal SalmonellaSurveillanceEpidemiologyFoodborne disease
spellingShingle Tongyu Wang
Weiwei Li
Ronghua Zhang
Jian Wen
Shuang Liu
Yuyan Jiang
Li Lin
Weiwei Chen
Jinjun Liang
Xiaochen Ma
Yijing Zhou
Haihong Han
Jikai Liu
Penghui Fan
Yunchang Guo
Linlin Wang
Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022
BMC Public Health
Nontyphoidal Salmonella
Surveillance
Epidemiology
Foodborne disease
title Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022
title_full Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022
title_fullStr Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022
title_full_unstemmed Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022
title_short Epidemiological features of nontyphoidal Salmonella infections reported to foodborne disease surveillance system in china, 2013–2022
title_sort epidemiological features of nontyphoidal salmonella infections reported to foodborne disease surveillance system in china 2013 2022
topic Nontyphoidal Salmonella
Surveillance
Epidemiology
Foodborne disease
url https://doi.org/10.1186/s12889-025-23439-z
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