Insulin Resistance: A Proinflammatory State Mediated by Lipid-Induced Signaling Dysfunction and Involved in Atherosclerotic Plaque Instability
The dysregulation of the insulin-glucose axis represents the crucial event in insulin resistance syndrome. Insulin resistance increases atherogenesis and atherosclerotic plaque instability by inducing proinflammatory activities on vascular and immune cells. This condition characterizes several disea...
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Main Authors: | Fabrizio Montecucco, Sabine Steffens, François Mach |
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Format: | Article |
Language: | English |
Published: |
Wiley
2008-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2008/767623 |
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