Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction

In 2021, 2.11 billion adults aged 25 and older worldwide were overweight or obese, with China having the highest number at 402 million. By 2050, the global population of overweight or obese adults is projected to rise to 3.8 billion, with China expected to account for 627 million of this total. More...

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Main Author: ZHANG Yifei, SHI Juan, XU Yuening
Format: Article
Language:zho
Published: Editorial Office of Journal of Diagnostics Concepts & Practice 2025-02-01
Series:Zhenduanxue lilun yu shijian
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Online Access:https://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1751006855390-332929424.pdf
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author ZHANG Yifei, SHI Juan, XU Yuening
author_facet ZHANG Yifei, SHI Juan, XU Yuening
author_sort ZHANG Yifei, SHI Juan, XU Yuening
collection DOAJ
description In 2021, 2.11 billion adults aged 25 and older worldwide were overweight or obese, with China having the highest number at 402 million. By 2050, the global population of overweight or obese adults is projected to rise to 3.8 billion, with China expected to account for 627 million of this total. Moreover, obesity is strongly associated with the occurrence and progression of various diseases, including cardiovascular diseases, cancers, and type 2 diabetes. Thus, the diagnosis and management of obesity have become a major global health challenge. However, traditional body mass index (BMI)-based diagnostic systems exhibit limitations in accurately reflecting abnormal fat distribution and metabolic dysfunction. Excessive visceral fat accumulation has been identified as a key factor in obesity-related metabolic disorders. Notably, visceral fat area (VFA), as an objective and quantifiable indicator for obesity assessment, demonstrates significant correlations with obesity and its comorbidities. Recent studies show that VFA outperforms BMI in the diagnosis and prediction of obesity and its associated comorbidities. Furthermore, VFA demonstrates superior value in evaluating the therapeutic efficacy of different interventions for obesity. Experience from China's Metabolic Management Center (MMC) has demonstrated the clinical value of VFA measured by standardized bioelectrical impedance analysis in obesity diagnosis and clinical mana-gement. In the future, the diagnosis and clinical management of obesity and its comorbidities should integrate multiple assessment methods incorporating multidimensional stratification analysis and personalized precision evaluation to further enhance comprehensive clinical management of obesity.
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spelling doaj-art-6df09eaff24d449bbff1d58918b4d53b2025-08-20T02:35:40ZzhoEditorial Office of Journal of Diagnostics Concepts & PracticeZhenduanxue lilun yu shijian1671-28702025-02-01240171310.16150/j.1671-2870.2025.01.002Current applications and prospects of visceral fat in obesity diagnosis and comorbidity predictionZHANG Yifei, SHI Juan, XU Yuening0Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai National Clinical Research Center for Metabolic Diseases; Key Laboratory for Endocrine and Metabolic Diseases, National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai 200025, ChinaIn 2021, 2.11 billion adults aged 25 and older worldwide were overweight or obese, with China having the highest number at 402 million. By 2050, the global population of overweight or obese adults is projected to rise to 3.8 billion, with China expected to account for 627 million of this total. Moreover, obesity is strongly associated with the occurrence and progression of various diseases, including cardiovascular diseases, cancers, and type 2 diabetes. Thus, the diagnosis and management of obesity have become a major global health challenge. However, traditional body mass index (BMI)-based diagnostic systems exhibit limitations in accurately reflecting abnormal fat distribution and metabolic dysfunction. Excessive visceral fat accumulation has been identified as a key factor in obesity-related metabolic disorders. Notably, visceral fat area (VFA), as an objective and quantifiable indicator for obesity assessment, demonstrates significant correlations with obesity and its comorbidities. Recent studies show that VFA outperforms BMI in the diagnosis and prediction of obesity and its associated comorbidities. Furthermore, VFA demonstrates superior value in evaluating the therapeutic efficacy of different interventions for obesity. Experience from China's Metabolic Management Center (MMC) has demonstrated the clinical value of VFA measured by standardized bioelectrical impedance analysis in obesity diagnosis and clinical mana-gement. In the future, the diagnosis and clinical management of obesity and its comorbidities should integrate multiple assessment methods incorporating multidimensional stratification analysis and personalized precision evaluation to further enhance comprehensive clinical management of obesity.https://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1751006855390-332929424.pdf|visceral fat|obesity|diagnosis|clinical management
spellingShingle ZHANG Yifei, SHI Juan, XU Yuening
Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
Zhenduanxue lilun yu shijian
|visceral fat|obesity|diagnosis|clinical management
title Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
title_full Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
title_fullStr Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
title_full_unstemmed Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
title_short Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
title_sort current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction
topic |visceral fat|obesity|diagnosis|clinical management
url https://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1751006855390-332929424.pdf
work_keys_str_mv AT zhangyifeishijuanxuyuening currentapplicationsandprospectsofvisceralfatinobesitydiagnosisandcomorbidityprediction