Purification, identification, and in silico screening of a multifunctional octapeptide from semen armeniacae glutelin-2 hydrolysates: restraining mechanisms to Keap1 and ACE, stability, and ferrous-transport efficiency

Purification, identification, and in silico screening of a multifunctional octapeptide from semen armeniacae glutelin-2 hydrolysates: restraining mechanisms to Keap1 and ACE, stability, and ferrous-transport efficiency

IntroductionSemen armeniacae is a traditional homologous material of medicine and food, but data on its multifunctional peptides are little.MethodsIn this study, semen armeniacae glutelin-2 was hydrolyzed by alcalase and trypsin assisted with ultrasound. Antihypertensive and antioxidant peptides wit...

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Main Authors: Ziqing Jin, Ling Dang, Yan Li, Chen Feng, Xinling Song, Zhihui Wei, Jie Liu, Hao Wang, Yichan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Nutrition
Subjects:
semen armeniacae glutelin-2 octapeptide
dual enzymolysis
angiotensin-I-converting enzyme
Keap1
inhibition mechanisms
antioxidant
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1571161/full
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https://www.frontiersin.org/articles/10.3389/fnut.2025.1571161/full

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