Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing (CPET) and 24-hour rhythm Holter in Tetralogy of Fallot (TOF) patients who underwent surgery.Materials and Methods: The study group consisted of patients over 6 years...

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Bibliographic Details
Main Authors: Elif Erolu, Figen Akalın, Nazife Reyyan Gök
Format: Article
Language:English
Published: Sakarya University 2025-03-01
Series:Sakarya Tıp Dergisi
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Online Access:https://dergipark.org.tr/tr/download/article-file/4199087
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Summary:Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing (CPET) and 24-hour rhythm Holter in Tetralogy of Fallot (TOF) patients who underwent surgery.Materials and Methods: The study group consisted of patients over 6 years of age who had undergone complete correction surgery for TOF, while the control group consisted of healthy children of a similar age group who did not have any heart disease. Echocardiography, 24-hour Holter monitoring and CPET were applied to both groups.Results: Study group included 14 patients who were operated on due to TOF and 9 healthy children as the control group. During echocardiographic examination; aortic diameter, pulmonary annulus, right ventricular (RV) systolic and diastolic areas were found to be significantly larger in the patient group (p=0.044, p=0.017, p=0.05, p=0.012 respectively). Myocardial performance index (Tei index-MPI) calculated from mitral and tricuspid valve annulus was found to be significantly higher in the patient group (p=0.05 for both). During CPET, stroke volume and VO2max levels were significantly smaller in patients (p=0.004, p=0.044 respectively).Conclusion: Although operated TOF patients are asymptomatic in the mid-term, the exercise capacity in these patients is lower than in healthy individuals and this decrease is related to right ventricular size and dysfunction.
ISSN:2146-409X