Engineering M13 bacteriophage to display HER2 mimotopes on pVIII for vaccine development

Engineering M13 bacteriophage to display HER2 mimotopes on pVIII for vaccine development

Abstract HER2-positive breast cancer is a subtype characterized by overexpression of the human epidermal growth factor receptor 2 (HER2), which is associated with aggressive tumor growth and poor prognosis. Peptide mimics of HER2 epitopes, recognized by tumor growth-inhibitory antibodies like trastu...

Full description

Saved in:
Bibliographic Details
Main Authors: Narmin Nazeri, Yadollah Bahrami, Ebrahim Barzegari, Mohammad Mohammadi, Fatemeh Kazemi-Lomedasht, Masoumeh Rajabibazl, Sara Mohammadzadeh
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
HER2
Trastuzumab
Mimotope
Phage display
Bacteriophage
Online Access:https://doi.org/10.1038/s41598-025-08032-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items