Metabolic Master Switch: Pyruvate Carboxylase Fuels Antimicrobial Resistance and Virulence in Foodborne <i>Staphylococcus aureus</i>

Metabolic Master Switch: Pyruvate Carboxylase Fuels Antimicrobial Resistance and Virulence in Foodborne <i>Staphylococcus aureus</i>

<i>Staphylococcus aureus</i>, a major cause of foodborne illness globally, presents significant challenges due to its multidrug resistance and biofilm-forming capabilities. Pyruvate carboxylase (PycA), a metabolic master switch linking glycolysis and the tricarboxylic acid (TCA) cycle, i...

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Bibliographic Details
Main Authors:	Zifeng Mai, Jiahui Li, Zeqiang Zhan, Xiaorong Tian, Wanwan Hou, Mu He, Chunlei Shi
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Foods
Subjects:	<i>Staphylococcus aureus</i> pyruvate carboxylase antimicrobial resistance biofilm TCA cycle purine metabolism
Online Access:	https://www.mdpi.com/2304-8158/14/15/2566
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