Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin
BackgroundAnemia is considered a risk factor for cardiovascular disease. However, there is little evidence regarding the relationship between hemoglobin (HB) and cerebral infarction after revascularization in patients with moyamoya disease (MMD). This study aimed to explore the relationship between...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1489430/full |
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| author | Haitao Wu Tingxuan Wang Fangbao Li Yue Bao Bin Lu Luo Li |
| author_facet | Haitao Wu Tingxuan Wang Fangbao Li Yue Bao Bin Lu Luo Li |
| author_sort | Haitao Wu |
| collection | DOAJ |
| description | BackgroundAnemia is considered a risk factor for cardiovascular disease. However, there is little evidence regarding the relationship between hemoglobin (HB) and cerebral infarction after revascularization in patients with moyamoya disease (MMD). This study aimed to explore the relationship between postoperative cerebral infarction and HB in patients with MMD and to establish a predictive model.MethodsDemographic information and different HB levels (the preoperative and postoperative HB, highest and lowest HB, and mean HB during hospitalization) of 112 patients with MMD were collected, of which 11 had cerebral infarction after revascularization.ResultsIn the binomial logistic regression analysis, low HB levels were an independent risk factor for cerebral infarction after revascularization, which also led to a worse long-term prognosis in patients with MMD. The risk factors, including Pre-HB, Post-HB, type of MMD, and hypertension (HTN), were incorporated into the receiver operating characteristic curve, which yielded an area under the curve (AUC) of 0.83.ConclusionThe prediction model was visualized using a nomogram, and a clinical decision curve was drawn to evaluate the net benefit of clinical decisions. |
| format | Article |
| id | doaj-art-6dda21d521bc41c9b70c080d104a7252 |
| institution | OA Journals |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neurology |
| spelling | doaj-art-6dda21d521bc41c9b70c080d104a72522025-08-20T01:48:25ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-01-011510.3389/fneur.2024.14894301489430Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobinHaitao Wu0Tingxuan Wang1Fangbao Li2Yue Bao3Bin Lu4Luo Li5Qingdao University Medical College, Qingdao University, Qingdao, ChinaQingdao University Medical College, Qingdao University, Qingdao, ChinaDalian Medical University, Dalian, ChinaDepartment of Neurosurgery, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, ChinaDepartment of Neurosurgery, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, ChinaDepartment of Neurosurgery, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, ChinaBackgroundAnemia is considered a risk factor for cardiovascular disease. However, there is little evidence regarding the relationship between hemoglobin (HB) and cerebral infarction after revascularization in patients with moyamoya disease (MMD). This study aimed to explore the relationship between postoperative cerebral infarction and HB in patients with MMD and to establish a predictive model.MethodsDemographic information and different HB levels (the preoperative and postoperative HB, highest and lowest HB, and mean HB during hospitalization) of 112 patients with MMD were collected, of which 11 had cerebral infarction after revascularization.ResultsIn the binomial logistic regression analysis, low HB levels were an independent risk factor for cerebral infarction after revascularization, which also led to a worse long-term prognosis in patients with MMD. The risk factors, including Pre-HB, Post-HB, type of MMD, and hypertension (HTN), were incorporated into the receiver operating characteristic curve, which yielded an area under the curve (AUC) of 0.83.ConclusionThe prediction model was visualized using a nomogram, and a clinical decision curve was drawn to evaluate the net benefit of clinical decisions.https://www.frontiersin.org/articles/10.3389/fneur.2024.1489430/fullmoyamoya diseasehemoglobinrevascularizationpostoperative cerebral infarctionprediction model |
| spellingShingle | Haitao Wu Tingxuan Wang Fangbao Li Yue Bao Bin Lu Luo Li Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin Frontiers in Neurology moyamoya disease hemoglobin revascularization postoperative cerebral infarction prediction model |
| title | Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin |
| title_full | Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin |
| title_fullStr | Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin |
| title_full_unstemmed | Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin |
| title_short | Low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease: development of a predictive model based on low hemoglobin |
| title_sort | low hemoglobin is associated with postoperative cerebral infarction in moyamoya disease development of a predictive model based on low hemoglobin |
| topic | moyamoya disease hemoglobin revascularization postoperative cerebral infarction prediction model |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1489430/full |
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