Features of the nasal microbiota in patients with allergic rhinitis: A review
The article analyzes the data of modern literature on the microbiota of ENT organs in normal and pathological conditions. The microbiota plays an important role in maintaining homeostasis by influencing metabolism, the immune system and human physiology. This complex of microorganisms includes bacte...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
ZAO "Consilium Medicum"
2024-10-01
|
| Series: | Consilium Medicum |
| Subjects: | |
| Online Access: | https://consilium.orscience.ru/2075-1753/article/viewFile/625571/pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841527610511720448 |
|---|---|
| author | Irina A. Saichenko Fatima P. Alidzhanova Daria V. Zyuzina Margarita A. Diukova Dayana G. Bajburdyan Kirill P. Raevskii |
| author_facet | Irina A. Saichenko Fatima P. Alidzhanova Daria V. Zyuzina Margarita A. Diukova Dayana G. Bajburdyan Kirill P. Raevskii |
| author_sort | Irina A. Saichenko |
| collection | DOAJ |
| description | The article analyzes the data of modern literature on the microbiota of ENT organs in normal and pathological conditions. The microbiota plays an important role in maintaining homeostasis by influencing metabolism, the immune system and human physiology. This complex of microorganisms includes bacteria, viruses and fungi that form the biofilm of otolaryngological organs, which prevents the penetration of pathogenic microorganisms. Different parts of the human upper respiratory tract have similar types of bacteria, but it differs dramatically at the level of families and genera. In addition, the balance of microbial flora depends on the immune system status, environmental factors, medication intake, age, race, lifestyle, as well as the health of other ENT organs. Changes in the nasal mucosa in allergic rhinitis are often associated with an increase in the content of bacteria. For example, Staphylococcus aureus can cause more severe nasal congestion in conjunction with protracted rhinitis and sinusitis. The production of bacterial proteinases contributes to easier penetration of allergens and activation of mucosal cells. The absence of microbiota can increase the response of the immune system and reduce the number of cells that contribute to the regulation of inflammation. This review presents an analysis of the composition of the normal microflora of otolaryngological organs and its effect on the occurrence of allergic rhinitis. |
| format | Article |
| id | doaj-art-6dd35c11e01344d394674f996c029bb7 |
| institution | Kabale University |
| issn | 2075-1753 2542-2170 |
| language | Russian |
| publishDate | 2024-10-01 |
| publisher | ZAO "Consilium Medicum" |
| record_format | Article |
| series | Consilium Medicum |
| spelling | doaj-art-6dd35c11e01344d394674f996c029bb72025-01-15T11:58:17ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702024-10-0126955756110.26442/20751753.2024.9.2026754783Features of the nasal microbiota in patients with allergic rhinitis: A reviewIrina A. Saichenko0https://orcid.org/0009-0009-5619-3255Fatima P. Alidzhanova1https://orcid.org/0009-0007-7878-7324Daria V. Zyuzina2https://orcid.org/0009-0002-2633-2866Margarita A. Diukova3https://orcid.org/0009-0007-2518-7739Dayana G. Bajburdyan4https://orcid.org/0009-0002-8330-0414Kirill P. Raevskii5https://orcid.org/0000-0002-9939-3443Almazov National Medical Research CentreKirov Military Medical AcademyKirov Military Medical AcademyMedical University “REAVIZ”Pavlov First Saint Petersburg State Medical UniversityKirov Military Medical AcademyThe article analyzes the data of modern literature on the microbiota of ENT organs in normal and pathological conditions. The microbiota plays an important role in maintaining homeostasis by influencing metabolism, the immune system and human physiology. This complex of microorganisms includes bacteria, viruses and fungi that form the biofilm of otolaryngological organs, which prevents the penetration of pathogenic microorganisms. Different parts of the human upper respiratory tract have similar types of bacteria, but it differs dramatically at the level of families and genera. In addition, the balance of microbial flora depends on the immune system status, environmental factors, medication intake, age, race, lifestyle, as well as the health of other ENT organs. Changes in the nasal mucosa in allergic rhinitis are often associated with an increase in the content of bacteria. For example, Staphylococcus aureus can cause more severe nasal congestion in conjunction with protracted rhinitis and sinusitis. The production of bacterial proteinases contributes to easier penetration of allergens and activation of mucosal cells. The absence of microbiota can increase the response of the immune system and reduce the number of cells that contribute to the regulation of inflammation. This review presents an analysis of the composition of the normal microflora of otolaryngological organs and its effect on the occurrence of allergic rhinitis.https://consilium.orscience.ru/2075-1753/article/viewFile/625571/pdfmicrobiotamicrobiomeallergic rhinitisrhinitisent organsallergensmicroorganismsmicroflorarespiratory tractnasal cavity |
| spellingShingle | Irina A. Saichenko Fatima P. Alidzhanova Daria V. Zyuzina Margarita A. Diukova Dayana G. Bajburdyan Kirill P. Raevskii Features of the nasal microbiota in patients with allergic rhinitis: A review Consilium Medicum microbiota microbiome allergic rhinitis rhinitis ent organs allergens microorganisms microflora respiratory tract nasal cavity |
| title | Features of the nasal microbiota in patients with allergic rhinitis: A review |
| title_full | Features of the nasal microbiota in patients with allergic rhinitis: A review |
| title_fullStr | Features of the nasal microbiota in patients with allergic rhinitis: A review |
| title_full_unstemmed | Features of the nasal microbiota in patients with allergic rhinitis: A review |
| title_short | Features of the nasal microbiota in patients with allergic rhinitis: A review |
| title_sort | features of the nasal microbiota in patients with allergic rhinitis a review |
| topic | microbiota microbiome allergic rhinitis rhinitis ent organs allergens microorganisms microflora respiratory tract nasal cavity |
| url | https://consilium.orscience.ru/2075-1753/article/viewFile/625571/pdf |
| work_keys_str_mv | AT irinaasaichenko featuresofthenasalmicrobiotainpatientswithallergicrhinitisareview AT fatimapalidzhanova featuresofthenasalmicrobiotainpatientswithallergicrhinitisareview AT dariavzyuzina featuresofthenasalmicrobiotainpatientswithallergicrhinitisareview AT margaritaadiukova featuresofthenasalmicrobiotainpatientswithallergicrhinitisareview AT dayanagbajburdyan featuresofthenasalmicrobiotainpatientswithallergicrhinitisareview AT kirillpraevskii featuresofthenasalmicrobiotainpatientswithallergicrhinitisareview |