Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection.
The relationship between postoperative physical changes and the development of homolateral neuropathic pain (HLNP) following mastectomy and lymph node resection remains poorly understood. In this study, we aimed to investigate whether early postoperative physical and symptom-based assessments could...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0326119 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850221686292480000 |
|---|---|
| author | Asall Kim Chunghwi Yi Myungki Ji Ui-Jae Hwang Jae-Young Lim Yujin Myung Eun Joo Choi Hee-Chul Shin Jaewon Beom |
| author_facet | Asall Kim Chunghwi Yi Myungki Ji Ui-Jae Hwang Jae-Young Lim Yujin Myung Eun Joo Choi Hee-Chul Shin Jaewon Beom |
| author_sort | Asall Kim |
| collection | DOAJ |
| description | The relationship between postoperative physical changes and the development of homolateral neuropathic pain (HLNP) following mastectomy and lymph node resection remains poorly understood. In this study, we aimed to investigate whether early postoperative physical and symptom-based assessments could predict HLNP occurrence at 4 months post-surgery. Fifty-seven breast cancer survivors were included, with HLNP defined as a painDETECT Questionnaire score ≥ 13 at 4 months. Independent variables included patient demographics, physical function metrics including pectoralis minor length index (PMI), and questionnaire-based evaluations at 1 month postoperatively. Multivariate logistic regression identified systemic therapy side effects (ST) (odds ratio [OR]: 1.056; 95% confidence interval [CI]: 1.015-1.098) and PMI (OR: 0.204; 95% CI: 0.043-0.977) as significant predictors of HLNP. Receiver operating characteristic curve analysis identified cutoff values of 23.81 for ST and 9.82 for PMI. Reconstruction type and adjuvant therapy influenced the correlation between PMI and the number of resected lymph nodes, unlike external rotation metrics. Early assessment of ST and PMI facilitates HLNP risk prediction following breast cancer surgery. Multimodal interventions, including targeted physical therapy, may mitigate HLNP risk, highlighting the importance of early postoperative care. |
| format | Article |
| id | doaj-art-6dd32af38198472daecb99de6bd10269 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-6dd32af38198472daecb99de6bd102692025-08-20T02:06:39ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01206e032611910.1371/journal.pone.0326119Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection.Asall KimChunghwi YiMyungki JiUi-Jae HwangJae-Young LimYujin MyungEun Joo ChoiHee-Chul ShinJaewon BeomThe relationship between postoperative physical changes and the development of homolateral neuropathic pain (HLNP) following mastectomy and lymph node resection remains poorly understood. In this study, we aimed to investigate whether early postoperative physical and symptom-based assessments could predict HLNP occurrence at 4 months post-surgery. Fifty-seven breast cancer survivors were included, with HLNP defined as a painDETECT Questionnaire score ≥ 13 at 4 months. Independent variables included patient demographics, physical function metrics including pectoralis minor length index (PMI), and questionnaire-based evaluations at 1 month postoperatively. Multivariate logistic regression identified systemic therapy side effects (ST) (odds ratio [OR]: 1.056; 95% confidence interval [CI]: 1.015-1.098) and PMI (OR: 0.204; 95% CI: 0.043-0.977) as significant predictors of HLNP. Receiver operating characteristic curve analysis identified cutoff values of 23.81 for ST and 9.82 for PMI. Reconstruction type and adjuvant therapy influenced the correlation between PMI and the number of resected lymph nodes, unlike external rotation metrics. Early assessment of ST and PMI facilitates HLNP risk prediction following breast cancer surgery. Multimodal interventions, including targeted physical therapy, may mitigate HLNP risk, highlighting the importance of early postoperative care.https://doi.org/10.1371/journal.pone.0326119 |
| spellingShingle | Asall Kim Chunghwi Yi Myungki Ji Ui-Jae Hwang Jae-Young Lim Yujin Myung Eun Joo Choi Hee-Chul Shin Jaewon Beom Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection. PLoS ONE |
| title | Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection. |
| title_full | Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection. |
| title_fullStr | Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection. |
| title_full_unstemmed | Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection. |
| title_short | Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection. |
| title_sort | pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection |
| url | https://doi.org/10.1371/journal.pone.0326119 |
| work_keys_str_mv | AT asallkim pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT chunghwiyi pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT myungkiji pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT uijaehwang pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT jaeyounglim pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT yujinmyung pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT eunjoochoi pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT heechulshin pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection AT jaewonbeom pectoralisminorlengthindexat1monthpostoperativecanpredicthomolateralneuropathicpain4monthsaftermastectomywithlymphnoderesection |