MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS
The placenta is the main organ that ensures the vital activity of the fetus during pregnancy. Studying the morphometric characteristics of chorionic villi allows us to better understand the changes that occur in the placenta in late pregnancy. Aim. To find out the percentage of chorionic villi o...
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Bukovynian State Medical University
2025-04-01
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| Series: | Неонатологія, хірургія та перинатальна медицина |
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| Online Access: | https://neonatology.bsmu.edu.ua/article/view/326035 |
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| author | О. Козар |
| author_facet | О. Козар |
| author_sort | О. Козар |
| collection | DOAJ |
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The placenta is the main organ that ensures the vital activity of the fetus during pregnancy. Studying the morphometric characteristics of chorionic villi allows us to better understand the changes that occur in the placenta in late pregnancy.
Aim. To find out the percentage of chorionic villi of the placenta at delivery after 40 weeks.
Materials and methods. The material for the study was 60 human placental preparations obtained as a result of childbirth: the main group - 30 placental preparations (births after 40 weeks of pregnancy), the comparison group - 30 placental preparations (births that occurred at 37-40 weeks of gestation). A set of classical methods of morphological examination was chosen for the study: morphometry, dissection, and photographic documentation. Digital copies of the image were analyzed using a legal copy of the specialized computer program ImageJ v1.53t. The obtained digital data were processed by statistical methods. The normality of the distribution according to the Shapiro-Wilki criterion did not deviate (p=0.05). Approval of the Bioethics Committee of Bukovinian State Medical University (protocol No. 1 of 09.21.2023). The study was performed as part of the research work of the Department of Obstetrics and Gynecology of Bukovinian State Medical University (Chernivtsi, Ukraine).
Results. The percentage of such villi as “early” and “late” stem villi, intermediate immature and mature villi, terminal and terminal “specialized villi” was estimated. Morphometric data show that in the main group, compared to the control group, the number of stem “late” choroidal villi is on average 2.8 times higher, the percentage of intermediate immature villi (2.67 times) and the percentage of intermediate mature villi (1.42 times) is significantly lower, the percentage of terminal villi is significantly higher, but the percentage of terminal “specialized” villi, on the contrary, is reduced.
Conclusions. In deliveries after 40 weeks, a change in the ratio of chorionic villi of the placenta is noted compared to deliveries at 37-40 weeks of gestation, in particular, the percentage of stem “late” villi and terminal villi increases, but the percentage of intermediate mature and immature villi, as well as terminal “specialized” villi decreases (%).
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| format | Article |
| id | doaj-art-6dd0ddca911a48b8975657b6d66bacdb |
| institution | Kabale University |
| issn | 2226-1230 2413-4260 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Bukovynian State Medical University |
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| series | Неонатологія, хірургія та перинатальна медицина |
| spelling | doaj-art-6dd0ddca911a48b8975657b6d66bacdb2025-08-20T03:59:16ZengBukovynian State Medical UniversityНеонатологія, хірургія та перинатальна медицина2226-12302413-42602025-04-01151(55)10.24061/2413-4260.XV.1.55.2025.12MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKSО. Козар0Bukovinian State Medical University The placenta is the main organ that ensures the vital activity of the fetus during pregnancy. Studying the morphometric characteristics of chorionic villi allows us to better understand the changes that occur in the placenta in late pregnancy. Aim. To find out the percentage of chorionic villi of the placenta at delivery after 40 weeks. Materials and methods. The material for the study was 60 human placental preparations obtained as a result of childbirth: the main group - 30 placental preparations (births after 40 weeks of pregnancy), the comparison group - 30 placental preparations (births that occurred at 37-40 weeks of gestation). A set of classical methods of morphological examination was chosen for the study: morphometry, dissection, and photographic documentation. Digital copies of the image were analyzed using a legal copy of the specialized computer program ImageJ v1.53t. The obtained digital data were processed by statistical methods. The normality of the distribution according to the Shapiro-Wilki criterion did not deviate (p=0.05). Approval of the Bioethics Committee of Bukovinian State Medical University (protocol No. 1 of 09.21.2023). The study was performed as part of the research work of the Department of Obstetrics and Gynecology of Bukovinian State Medical University (Chernivtsi, Ukraine). Results. The percentage of such villi as “early” and “late” stem villi, intermediate immature and mature villi, terminal and terminal “specialized villi” was estimated. Morphometric data show that in the main group, compared to the control group, the number of stem “late” choroidal villi is on average 2.8 times higher, the percentage of intermediate immature villi (2.67 times) and the percentage of intermediate mature villi (1.42 times) is significantly lower, the percentage of terminal villi is significantly higher, but the percentage of terminal “specialized” villi, on the contrary, is reduced. Conclusions. In deliveries after 40 weeks, a change in the ratio of chorionic villi of the placenta is noted compared to deliveries at 37-40 weeks of gestation, in particular, the percentage of stem “late” villi and terminal villi increases, but the percentage of intermediate mature and immature villi, as well as terminal “specialized” villi decreases (%). https://neonatology.bsmu.edu.ua/article/view/326035Labor after 40 weeks; Trophoblast; Chorionic villi; Placenta; Pregnancy |
| spellingShingle | О. Козар MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS Неонатологія, хірургія та перинатальна медицина Labor after 40 weeks; Trophoblast; Chorionic villi; Placenta; Pregnancy |
| title | MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS |
| title_full | MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS |
| title_fullStr | MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS |
| title_full_unstemmed | MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS |
| title_short | MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS |
| title_sort | morphometric parameters of placental chorionic villi in labor after 40 weeks |
| topic | Labor after 40 weeks; Trophoblast; Chorionic villi; Placenta; Pregnancy |
| url | https://neonatology.bsmu.edu.ua/article/view/326035 |
| work_keys_str_mv | AT okozar morphometricparametersofplacentalchorionicvilliinlaborafter40weeks |