Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network

The present study proposes a Bayesian-optimized back-propagation (BP) neural network framework for predicting the tribological performance of hyaluronic acid (HA) aqueous solutions under hydrodynamic lubrication conditions. The model addresses the complex rheological behavior of HA and limitations o...

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Main Authors: Xia Li, Feng Guo
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Lubricants
Subjects:
Online Access:https://www.mdpi.com/2075-4442/13/5/215
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author Xia Li
Feng Guo
author_facet Xia Li
Feng Guo
author_sort Xia Li
collection DOAJ
description The present study proposes a Bayesian-optimized back-propagation (BP) neural network framework for predicting the tribological performance of hyaluronic acid (HA) aqueous solutions under hydrodynamic lubrication conditions. The model addresses the complex rheological behavior of HA and limitations of traditional trial-and-error methods. It integrates four operational parameters—applied load, sliding speed, fluid viscosity and contact surface inclination. These enable the simultaneous prediction of two critical lubrication characteristics: film thickness and load-carrying capacity. Bayesian optimization was used to automate hyperparameter tuning. This can significantly improve computational efficiency. The optimized model showed a coefficient of determination (R<sup>2</sup>) of 0.938 and a mean square error (MSE) of 0.0025 on the test dataset, indicating its ability for accurate prediction. The results indicated a significant positive correlation between HA viscosity and lubrication performance. This framework can be used as a screening tool for HA-based lubricants. The integration of machine learning with biotribology may offer opportunities to improve data-driven approaches to analyzing complex fluid behavior, where traditional models have limitations.
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spelling doaj-art-6dcc73d6ae3c4e59ada34bc70621ff5a2025-08-20T01:56:19ZengMDPI AGLubricants2075-44422025-05-0113521510.3390/lubricants13050215Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP NetworkXia Li0Feng Guo1School of Mechanical and Automotive Engineering, Qingdao University of Technology, Qingdao 266520, ChinaDepartment of Vehicle Engineering, Yantai Automobile Engineering Professional College, Yantai 265599, ChinaThe present study proposes a Bayesian-optimized back-propagation (BP) neural network framework for predicting the tribological performance of hyaluronic acid (HA) aqueous solutions under hydrodynamic lubrication conditions. The model addresses the complex rheological behavior of HA and limitations of traditional trial-and-error methods. It integrates four operational parameters—applied load, sliding speed, fluid viscosity and contact surface inclination. These enable the simultaneous prediction of two critical lubrication characteristics: film thickness and load-carrying capacity. Bayesian optimization was used to automate hyperparameter tuning. This can significantly improve computational efficiency. The optimized model showed a coefficient of determination (R<sup>2</sup>) of 0.938 and a mean square error (MSE) of 0.0025 on the test dataset, indicating its ability for accurate prediction. The results indicated a significant positive correlation between HA viscosity and lubrication performance. This framework can be used as a screening tool for HA-based lubricants. The integration of machine learning with biotribology may offer opportunities to improve data-driven approaches to analyzing complex fluid behavior, where traditional models have limitations.https://www.mdpi.com/2075-4442/13/5/215hyaluronic acid (HA)BP neural networkBayesian optimizationfilm thicknessload-carrying capacity
spellingShingle Xia Li
Feng Guo
Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network
Lubricants
hyaluronic acid (HA)
BP neural network
Bayesian optimization
film thickness
load-carrying capacity
title Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network
title_full Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network
title_fullStr Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network
title_full_unstemmed Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network
title_short Prediction of Lubrication Performance of Hyaluronic Acid Aqueous Solutions Using a Bayesian-Optimized BP Network
title_sort prediction of lubrication performance of hyaluronic acid aqueous solutions using a bayesian optimized bp network
topic hyaluronic acid (HA)
BP neural network
Bayesian optimization
film thickness
load-carrying capacity
url https://www.mdpi.com/2075-4442/13/5/215
work_keys_str_mv AT xiali predictionoflubricationperformanceofhyaluronicacidaqueoussolutionsusingabayesianoptimizedbpnetwork
AT fengguo predictionoflubricationperformanceofhyaluronicacidaqueoussolutionsusingabayesianoptimizedbpnetwork