Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review.

Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review.

<h4>Background</h4>Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomark...

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Bibliographic Details
Main Authors: Miranta Antoniou, Andrea L Jorgensen, Ruwanthi Kolamunnage-Dona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0149803&type=printable
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