Ichthyosis Fetalis in a Lacaune Lamb

ABSTRACT Ichthyosis (inherited congenital condition) is a heterogeneous group of skin cornification and keratinization disorders. Ichthyosis can affect animal and human and characterized by an excessive amount of superficial scale on the skin. A male Lacaune lamb was born alive from a primiparous ew...

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Main Authors: Arman Shokri, Afshin Raoofi, Sara Shokrpoor
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Veterinary Medicine and Science
Subjects:
Online Access:https://doi.org/10.1002/vms3.70364
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author Arman Shokri
Afshin Raoofi
Sara Shokrpoor
author_facet Arman Shokri
Afshin Raoofi
Sara Shokrpoor
author_sort Arman Shokri
collection DOAJ
description ABSTRACT Ichthyosis (inherited congenital condition) is a heterogeneous group of skin cornification and keratinization disorders. Ichthyosis can affect animal and human and characterized by an excessive amount of superficial scale on the skin. A male Lacaune lamb was born alive from a primiparous ewe but it was unable to stand and it was in lateral recumbency and died 12 h after birth. Skin abnormalities included all over hyperkeratosis, cracking in some parts of the body like head and neck. In histopathological investigation of the cutaneous lesions, there was moderate‐to‐severe thickening of the stratum corneum, with a compact and laminated pattern of orthokeratotic hyperkeratosis, whereas no abnormalities were observed in the other layers of the epidermis. Ichthyosis was diagnosed on the basis of clinical and histopathological findings. In conclusion, ichthyosis in lambs can occur in different forms, but further studies and investigations are needed to accurate classification of this condition in lamb.
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spelling doaj-art-6dbad54ae04c44a480fc708d720854882025-08-20T03:12:08ZengWileyVeterinary Medicine and Science2053-10952025-05-01113n/an/a10.1002/vms3.70364Ichthyosis Fetalis in a Lacaune LambArman Shokri0Afshin Raoofi1Sara Shokrpoor2Department of Internal Medicine, Faculty of Veterinary Medicine University of Tehran Tehran IranDepartment of Internal Medicine, Faculty of Veterinary Medicine University of Tehran Tehran IranDepartment of Pathobiology, Faculty of Veterinary Medicine University of Tehran Tehran IranABSTRACT Ichthyosis (inherited congenital condition) is a heterogeneous group of skin cornification and keratinization disorders. Ichthyosis can affect animal and human and characterized by an excessive amount of superficial scale on the skin. A male Lacaune lamb was born alive from a primiparous ewe but it was unable to stand and it was in lateral recumbency and died 12 h after birth. Skin abnormalities included all over hyperkeratosis, cracking in some parts of the body like head and neck. In histopathological investigation of the cutaneous lesions, there was moderate‐to‐severe thickening of the stratum corneum, with a compact and laminated pattern of orthokeratotic hyperkeratosis, whereas no abnormalities were observed in the other layers of the epidermis. Ichthyosis was diagnosed on the basis of clinical and histopathological findings. In conclusion, ichthyosis in lambs can occur in different forms, but further studies and investigations are needed to accurate classification of this condition in lamb.https://doi.org/10.1002/vms3.70364hyperkeratosisichthyosisLacaunelamb
spellingShingle Arman Shokri
Afshin Raoofi
Sara Shokrpoor
Ichthyosis Fetalis in a Lacaune Lamb
Veterinary Medicine and Science
hyperkeratosis
ichthyosis
Lacaune
lamb
title Ichthyosis Fetalis in a Lacaune Lamb
title_full Ichthyosis Fetalis in a Lacaune Lamb
title_fullStr Ichthyosis Fetalis in a Lacaune Lamb
title_full_unstemmed Ichthyosis Fetalis in a Lacaune Lamb
title_short Ichthyosis Fetalis in a Lacaune Lamb
title_sort ichthyosis fetalis in a lacaune lamb
topic hyperkeratosis
ichthyosis
Lacaune
lamb
url https://doi.org/10.1002/vms3.70364
work_keys_str_mv AT armanshokri ichthyosisfetalisinalacaunelamb
AT afshinraoofi ichthyosisfetalisinalacaunelamb
AT sarashokrpoor ichthyosisfetalisinalacaunelamb