Research progress in the construction of animal models of autoimmune thyroiditis
Autoimmune thyroiditis (AIT), also known as Hashimoto’s thyroiditis (HT), is an autoimmune disease that is characterised by elevated thyroid-specific antibody titres. The incidence of AIT is increasing year over year, making it urgent to establish a suitable animal model for this condition, in order...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
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| Series: | Autoimmunity |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/08916934.2024.2317190 |
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| _version_ | 1850107750183337984 |
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| author | Ke Liu Pei Zhang Ling Zhou Lin Han Linhua Zhao Xiaotong Yu |
| author_facet | Ke Liu Pei Zhang Ling Zhou Lin Han Linhua Zhao Xiaotong Yu |
| author_sort | Ke Liu |
| collection | DOAJ |
| description | Autoimmune thyroiditis (AIT), also known as Hashimoto’s thyroiditis (HT), is an autoimmune disease that is characterised by elevated thyroid-specific antibody titres. The incidence of AIT is increasing year over year, making it urgent to establish a suitable animal model for this condition, in order to better explore its pathogenesis and potential pharmaceutical mechanisms for treatment. Owing to a lack of basic research on this disease, problems such as disparate modelling methods with unclear and varying success rates make it difficult for researchers to obtain effective information on AIT in the short term. This report summarises and analyzes the current literature on AIT and combines actual operability to explain the selection and specific implementation processes behind the uses of different modelling approaches, to provide a better overall understanding of autoimmune thyroid diseases. |
| format | Article |
| id | doaj-art-6db7d98d98e942f2aef5b7399103bdd7 |
| institution | OA Journals |
| issn | 0891-6934 1607-842X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Autoimmunity |
| spelling | doaj-art-6db7d98d98e942f2aef5b7399103bdd72025-08-20T02:38:31ZengTaylor & Francis GroupAutoimmunity0891-69341607-842X2024-12-0157110.1080/08916934.2024.2317190Research progress in the construction of animal models of autoimmune thyroiditisKe Liu0Pei Zhang1Ling Zhou2Lin Han3Linhua Zhao4Xiaotong Yu5Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaBeijing University of Chinese Medicine, Beijing, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaAutoimmune thyroiditis (AIT), also known as Hashimoto’s thyroiditis (HT), is an autoimmune disease that is characterised by elevated thyroid-specific antibody titres. The incidence of AIT is increasing year over year, making it urgent to establish a suitable animal model for this condition, in order to better explore its pathogenesis and potential pharmaceutical mechanisms for treatment. Owing to a lack of basic research on this disease, problems such as disparate modelling methods with unclear and varying success rates make it difficult for researchers to obtain effective information on AIT in the short term. This report summarises and analyzes the current literature on AIT and combines actual operability to explain the selection and specific implementation processes behind the uses of different modelling approaches, to provide a better overall understanding of autoimmune thyroid diseases.https://www.tandfonline.com/doi/10.1080/08916934.2024.2317190Hashimoto’s thyroiditisautoimmune thyroiditisanimal modelautoimmune diseasethyroid |
| spellingShingle | Ke Liu Pei Zhang Ling Zhou Lin Han Linhua Zhao Xiaotong Yu Research progress in the construction of animal models of autoimmune thyroiditis Autoimmunity Hashimoto’s thyroiditis autoimmune thyroiditis animal model autoimmune disease thyroid |
| title | Research progress in the construction of animal models of autoimmune thyroiditis |
| title_full | Research progress in the construction of animal models of autoimmune thyroiditis |
| title_fullStr | Research progress in the construction of animal models of autoimmune thyroiditis |
| title_full_unstemmed | Research progress in the construction of animal models of autoimmune thyroiditis |
| title_short | Research progress in the construction of animal models of autoimmune thyroiditis |
| title_sort | research progress in the construction of animal models of autoimmune thyroiditis |
| topic | Hashimoto’s thyroiditis autoimmune thyroiditis animal model autoimmune disease thyroid |
| url | https://www.tandfonline.com/doi/10.1080/08916934.2024.2317190 |
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