Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells

Nitrosative stress is defined as a condition in which oxidative stress accompanies the presence of excess NO and they both may alter the integrity of the red blood cell membrane (RBC). In this study, age- and sex-related effects of nitrosative stress on the membrane osmotic fragility of RBC were inv...

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Main Authors: Kemer Serkan, Usanmaz Suzan Emel, Oztorun Hande Selvi, Bogaoglu Aylin Ecem, Sannah Beyan, Sanlı Fatma, Aslan Gamze, Bilici Nisanur, Karayilan Nurcan, Ciftci Rabia Isilay, Varli Murat, Demirel-Yilmaz Emine
Format: Article
Language:English
Published: De Gruyter 2025-04-01
Series:Türk Biyokimya Dergisi
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Online Access:https://doi.org/10.1515/tjb-2024-0121
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author Kemer Serkan
Usanmaz Suzan Emel
Oztorun Hande Selvi
Bogaoglu Aylin Ecem
Sannah Beyan
Sanlı Fatma
Aslan Gamze
Bilici Nisanur
Karayilan Nurcan
Ciftci Rabia Isilay
Varli Murat
Demirel-Yilmaz Emine
author_facet Kemer Serkan
Usanmaz Suzan Emel
Oztorun Hande Selvi
Bogaoglu Aylin Ecem
Sannah Beyan
Sanlı Fatma
Aslan Gamze
Bilici Nisanur
Karayilan Nurcan
Ciftci Rabia Isilay
Varli Murat
Demirel-Yilmaz Emine
author_sort Kemer Serkan
collection DOAJ
description Nitrosative stress is defined as a condition in which oxidative stress accompanies the presence of excess NO and they both may alter the integrity of the red blood cell membrane (RBC). In this study, age- and sex-related effects of nitrosative stress on the membrane osmotic fragility of RBC were investigated using NO and superoxide donors in the RBC isolated from participants.
format Article
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issn 1303-829X
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publishDate 2025-04-01
publisher De Gruyter
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series Türk Biyokimya Dergisi
spelling doaj-art-6db1989340944d4aa3cfc94aef10e1a62025-08-20T01:48:38ZengDe GruyterTürk Biyokimya Dergisi1303-829X2025-04-0150227128210.1515/tjb-2024-0121Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cellsKemer Serkan0Usanmaz Suzan Emel1Oztorun Hande Selvi2Bogaoglu Aylin Ecem3Sannah Beyan4Sanlı Fatma5Aslan Gamze6Bilici Nisanur7Karayilan Nurcan8Ciftci Rabia Isilay9Varli Murat10Demirel-Yilmaz Emine11Department of Medical Pharmacology, University of Health Sciences, Gulhane Faculty of Medicine, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Geriatrics, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Geriatrics, Faculty of Medicine, Ankara University, Ankara, TürkiyeDepartment of Medical Pharmacology, Faculty of Medicine, Ankara University, Ankara, TürkiyeNitrosative stress is defined as a condition in which oxidative stress accompanies the presence of excess NO and they both may alter the integrity of the red blood cell membrane (RBC). In this study, age- and sex-related effects of nitrosative stress on the membrane osmotic fragility of RBC were investigated using NO and superoxide donors in the RBC isolated from participants.https://doi.org/10.1515/tjb-2024-0121erythrocyte osmotic fragilitynitric oxidenitrosative stressoxidative stress
spellingShingle Kemer Serkan
Usanmaz Suzan Emel
Oztorun Hande Selvi
Bogaoglu Aylin Ecem
Sannah Beyan
Sanlı Fatma
Aslan Gamze
Bilici Nisanur
Karayilan Nurcan
Ciftci Rabia Isilay
Varli Murat
Demirel-Yilmaz Emine
Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
Türk Biyokimya Dergisi
erythrocyte osmotic fragility
nitric oxide
nitrosative stress
oxidative stress
title Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
title_full Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
title_fullStr Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
title_full_unstemmed Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
title_short Age and sex-dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
title_sort age and sex dependent effects of nitrosative stress on the osmotic fragility of human red blood cells
topic erythrocyte osmotic fragility
nitric oxide
nitrosative stress
oxidative stress
url https://doi.org/10.1515/tjb-2024-0121
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