Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
Because of the ability to metabolize a large number of electron acceptors such as nitrate, nitrite, fumarate, and metal oxides, Shewanella species have attracted much attention in recent years. Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Genetics Research |
| Online Access: | http://dx.doi.org/10.1155/2021/9953783 |
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| author | Dewu Ding Meineng Wang Meili Wu Chengzhi Gan Pu Wu |
| author_facet | Dewu Ding Meineng Wang Meili Wu Chengzhi Gan Pu Wu |
| author_sort | Dewu Ding |
| collection | DOAJ |
| description | Because of the ability to metabolize a large number of electron acceptors such as nitrate, nitrite, fumarate, and metal oxides, Shewanella species have attracted much attention in recent years. Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and their interactions which will dynamically change across different environmental conditions in cells. Therefore, functional analysis of condition-specific molecular networks can reveal biological information on electron transfer processes. By integrating expression data and molecular networks, we constructed condition-specific molecular networks for Shewanella piezotolerans WP3. We then identified condition-specific key genes and studied their potential functions with an emphasis on their roles in electron transfer processes. Functional module analysis showed that different flagellar assembly modules appeared under these conditions and suggested that flagellar proteins are important for these conditions. We also identified the electron transfer modules underlying these various environmental conditions. The present results could help with screening electron transfer genes and understanding electron transfer processes under various environmental conditions for the Shewanella species. |
| format | Article |
| id | doaj-art-6da9fcdedb1f46cd87032e727dbc1a4b |
| institution | OA Journals |
| issn | 1469-5073 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Genetics Research |
| spelling | doaj-art-6da9fcdedb1f46cd87032e727dbc1a4b2025-08-20T02:06:12ZengWileyGenetics Research1469-50732021-01-01202110.1155/2021/99537839953783Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3Dewu Ding0Meineng Wang1Meili Wu2Chengzhi Gan3Pu Wu4School of Mathematics and Computer Science, Yichun University, Yichun 336000, ChinaSchool of Mathematics and Computer Science, Yichun University, Yichun 336000, ChinaLibrary of Yichun Vocational Technical College, Yichun 336000, ChinaSchool of Mathematics and Computer Science, Yichun University, Yichun 336000, ChinaSchool of Mathematics and Computer Science, Chizhou University, Chizhou 247000, ChinaBecause of the ability to metabolize a large number of electron acceptors such as nitrate, nitrite, fumarate, and metal oxides, Shewanella species have attracted much attention in recent years. Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and their interactions which will dynamically change across different environmental conditions in cells. Therefore, functional analysis of condition-specific molecular networks can reveal biological information on electron transfer processes. By integrating expression data and molecular networks, we constructed condition-specific molecular networks for Shewanella piezotolerans WP3. We then identified condition-specific key genes and studied their potential functions with an emphasis on their roles in electron transfer processes. Functional module analysis showed that different flagellar assembly modules appeared under these conditions and suggested that flagellar proteins are important for these conditions. We also identified the electron transfer modules underlying these various environmental conditions. The present results could help with screening electron transfer genes and understanding electron transfer processes under various environmental conditions for the Shewanella species.http://dx.doi.org/10.1155/2021/9953783 |
| spellingShingle | Dewu Ding Meineng Wang Meili Wu Chengzhi Gan Pu Wu Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 Genetics Research |
| title | Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 |
| title_full | Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 |
| title_fullStr | Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 |
| title_full_unstemmed | Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 |
| title_short | Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 |
| title_sort | condition specific molecular network analysis revealed that flagellar proteins are involved in electron transfer processes of shewanella piezotolerans wp3 |
| url | http://dx.doi.org/10.1155/2021/9953783 |
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