In situ detection of piRNA‐651 in exosomes and cells for cancer diagnosis by a new gold nanoparticle nucleic acid probe

In situ detection of piRNA‐651 in exosomes and cells for cancer diagnosis by a new gold nanoparticle nucleic acid probe

Abstract Increasing studies have demonstrated that PIWI‐interacting RNAs (piRNAs) in circulating exosomes can serve as novel molecular biomarkers for tumor liquid biopsy. However, methods for in situ detection of piRNAs encased in exosomes are limited. In this study, we designed a spherical nucleic...

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Bibliographic Details
Main Authors: Qin‐Xin Gao, Qian‐Qian Wu, Zhi‐Ying Dong, Xiao‐Yuan Qin, Lin‐Yan Zhai, Bao‐Ping Xie, Wen‐Jun Duan
Format: Article
Language:English
Published: Wiley-VCH 2025-01-01
Series:Interdisciplinary Medicine
Subjects:
breast cancer diagnosis
in situ detection
piR‐651
plasma exosomes
spherical nucleic acid
Online Access:https://doi.org/10.1002/INMD.20240058
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