Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type
Background: ACC can occasionally undergo dedifferentiation also referred to as high-grade transformation (ACC-HGT). However, ACC-HGT can also undergo transformation to adenocarcinomas which are not poorly differentiated. ACC-HGT is generally considered to be an aggressive variant of ACC, even more t...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-CLO-2010-0547 |
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| _version_ | 1832561222717800448 |
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| author | Ana Flávia Costa Albina Altemani Hedy Vékony Elisabeth Bloemena Florentino Fresno Carlos Suárez José Luis Llorente Mario Hermsen |
| author_facet | Ana Flávia Costa Albina Altemani Hedy Vékony Elisabeth Bloemena Florentino Fresno Carlos Suárez José Luis Llorente Mario Hermsen |
| author_sort | Ana Flávia Costa |
| collection | DOAJ |
| description | Background: ACC can occasionally undergo dedifferentiation also referred to as high-grade transformation (ACC-HGT). However, ACC-HGT can also undergo transformation to adenocarcinomas which are not poorly differentiated. ACC-HGT is generally considered to be an aggressive variant of ACC, even more than solid ACC. This study was aimed to describe the genetic changes of ACC-HGT in relation to clinico-pathological features and to compare results to solid ACC. |
| format | Article |
| id | doaj-art-6da66b5166a04214b08aba77295749a3 |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-6da66b5166a04214b08aba77295749a32025-02-03T01:25:41ZengWileyAnalytical Cellular Pathology2210-71772210-71852010-01-01335-621722810.3233/ACP-CLO-2010-0547Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid TypeAna Flávia Costa0Albina Altemani1Hedy Vékony2Elisabeth Bloemena3Florentino Fresno4Carlos Suárez5José Luis Llorente6Mario Hermsen7Department of Pathology, University of Campinas/UNICAMP, Campinas, BrazilDepartment of Pathology, University of Campinas/UNICAMP, Campinas, BrazilDepartment of Pathology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Pathology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Pathology, IUOPA, Hospital Universitario Central de Asturias, Oviedo, SpainDepartment of Otolaryngology, IUOPA, Hospital Universitario Central de Asturias, Oviedo, SpainDepartment of Otolaryngology, IUOPA, Hospital Universitario Central de Asturias, Oviedo, SpainDepartment of Otolaryngology, IUOPA, Hospital Universitario Central de Asturias, Oviedo, SpainBackground: ACC can occasionally undergo dedifferentiation also referred to as high-grade transformation (ACC-HGT). However, ACC-HGT can also undergo transformation to adenocarcinomas which are not poorly differentiated. ACC-HGT is generally considered to be an aggressive variant of ACC, even more than solid ACC. This study was aimed to describe the genetic changes of ACC-HGT in relation to clinico-pathological features and to compare results to solid ACC.http://dx.doi.org/10.3233/ACP-CLO-2010-0547 |
| spellingShingle | Ana Flávia Costa Albina Altemani Hedy Vékony Elisabeth Bloemena Florentino Fresno Carlos Suárez José Luis Llorente Mario Hermsen Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type Analytical Cellular Pathology |
| title | Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type |
| title_full | Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type |
| title_fullStr | Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type |
| title_full_unstemmed | Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type |
| title_short | Genetic Profile of Adenoid Cystic Carcinomas (ACC) with High-Grade Transformation versus Solid Type |
| title_sort | genetic profile of adenoid cystic carcinomas acc with high grade transformation versus solid type |
| url | http://dx.doi.org/10.3233/ACP-CLO-2010-0547 |
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