Conservation of dark CPD photolyase function in blind cavefish

Abstract DNA damage is generated by various environmental stressors and so DNA repair systems must inevitably adapt to changing environments. Photolyases represent a highly conserved class of enzymes which repair UV-induced covalent crosslinks between adjacent pyrimidine bases (CPD and 6-4 photoprod...

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Main Authors: Hongxiang Li, Carina Scheitle, Giuseppe Di Mauro, Silvia Fuselli, Susanne Fritsch-Decker, Takeshi Todo, Carsten Weiss, Daniela Vallone, Tilman Lamparter, Cristiano Bertolucci, Nicholas S. Foulkes
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62795-7
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