Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney
As a member of steroid/thyroid hormone receptor superfamily， chicken ovalbumin upstream promoter transcription factor II （COUP-TFII） is an orphan receptor since its ligand has remained unknown. It has been established that COUP-TFII participates in many pathophysiological processes of organic develo...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2022-11-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.11.011 |
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| _version_ | 1850143342585708544 |
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| author | Zuo Xiao-lin Zhao Xiao-dong Ren Jian-min Xiao Xiao-yan |
| author_facet | Zuo Xiao-lin Zhao Xiao-dong Ren Jian-min Xiao Xiao-yan |
| author_sort | Zuo Xiao-lin |
| collection | DOAJ |
| description | As a member of steroid/thyroid hormone receptor superfamily， chicken ovalbumin upstream promoter transcription factor II （COUP-TFII） is an orphan receptor since its ligand has remained unknown. It has been established that COUP-TFII participates in many pathophysiological processes of organic development & differentiation， metabolic regulations， regulating angiogenesis & lymphangiogenesis， carcinogenesis or suppressing cancerous proliferation & metastasis in different tumor microenvironments. Distributed mostly in glomerulus， distal tubule， collecting tubule and Bowman capsule in kidney， COUP-TFII modulates renal formation as well as initiation and progression of various renal diseases. This review summarized the latest advances of COUP-TFII in renal development， renal tumor， acute renal injury and renal fibrosis. |
| format | Article |
| id | doaj-art-6da47dd95e9c4c57be3015aaa43937fd |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-11-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-6da47dd95e9c4c57be3015aaa43937fd2025-08-20T02:28:45ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-11-012294795132859643Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidneyZuo Xiao-linZhao Xiao-dongRen Jian-minXiao Xiao-yanAs a member of steroid/thyroid hormone receptor superfamily， chicken ovalbumin upstream promoter transcription factor II （COUP-TFII） is an orphan receptor since its ligand has remained unknown. It has been established that COUP-TFII participates in many pathophysiological processes of organic development & differentiation， metabolic regulations， regulating angiogenesis & lymphangiogenesis， carcinogenesis or suppressing cancerous proliferation & metastasis in different tumor microenvironments. Distributed mostly in glomerulus， distal tubule， collecting tubule and Bowman capsule in kidney， COUP-TFII modulates renal formation as well as initiation and progression of various renal diseases. This review summarized the latest advances of COUP-TFII in renal development， renal tumor， acute renal injury and renal fibrosis.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.11.011Chicken ovalbumin upstream promoter transcription factor IIKidney differentiationRenal cell carcinomaKidney disease |
| spellingShingle | Zuo Xiao-lin Zhao Xiao-dong Ren Jian-min Xiao Xiao-yan Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney Linchuang shenzangbing zazhi Chicken ovalbumin upstream promoter transcription factor II Kidney differentiation Renal cell carcinoma Kidney disease |
| title | Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney |
| title_full | Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney |
| title_fullStr | Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney |
| title_full_unstemmed | Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney |
| title_short | Role and mechanism of chicken ovalbumin upstream promoter transcription factor II in kidney |
| title_sort | role and mechanism of chicken ovalbumin upstream promoter transcription factor ii in kidney |
| topic | Chicken ovalbumin upstream promoter transcription factor II Kidney differentiation Renal cell carcinoma Kidney disease |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.11.011 |
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