Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway
Background: Pulse pressure index as a function of pulse pressure divided by systolic blood pressure served is a useful predictor of cardiovascular events. Objectives: Our aim was to assess the pulse pressure index as a discriminating variable of predicting cardiovascular events in untreated or hyper...
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University of Anbar
2019-06-01
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| Series: | Al-Anbar Medical Journal |
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| Online Access: | https://amj.uoanbar.edu.iq/article_170879_ede6ed32f405035bcdd2127a19b882d9.pdf |
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| author | Marwan S. Al-Nime Ismail I. Hussein Yagub S. Saleh |
| author_facet | Marwan S. Al-Nime Ismail I. Hussein Yagub S. Saleh |
| author_sort | Marwan S. Al-Nime |
| collection | DOAJ |
| description | Background: Pulse pressure index as a function of pulse pressure divided by systolic blood pressure served is a useful predictor of cardiovascular events. Objectives: Our aim was to assess the pulse pressure index as a discriminating variable of predicting cardiovascular events in untreated or hypertensive patients and treated with one member of angiotensin converting enzyme inhibitors or angiotensin receptor blockers by using the scores of Framingham study. Materials and methods: This observational cross-sectional study, including 140 patients who grouped into; Group I (n = 30): untreated hypertensive patients; Group II (n = 60): patients treated with angiotensin receptor blockers; and Group III (n = 50): patients treated with angiotensin converting enzyme inhibitors. Anthropometric measurements, lipid profile, and blood pressure were determined. The probability of ten-year of cardiovascular events was calculated according to the Framingham study scores using The University of Edinburgh Cardiovascular Risk Calculator (http://cvrisk.mvm.ed.ac.uk/calculator/calc.asp). Results: There is a non-significant difference between Groups and within Groups of age, smoking habit, and the values of the cardio metabolic risk factors. Pulse pressure index as an independent risk factor found to be a significant discriminator of 10-year prediction of cardiovascular events by using the receiving operating characteristic curves. Conclusion: The pulse pressure index is a useful discriminator of predicting cardiovascular events, and it will improve the Framingham prediction risk among hypertensive patients. |
| format | Article |
| id | doaj-art-6d9409c6cfc74e7ea0175d478f4b97a5 |
| institution | DOAJ |
| issn | 2706-6207 2664-3154 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | University of Anbar |
| record_format | Article |
| series | Al-Anbar Medical Journal |
| spelling | doaj-art-6d9409c6cfc74e7ea0175d478f4b97a52025-08-20T02:49:19ZengUniversity of AnbarAl-Anbar Medical Journal2706-62072664-31542019-06-011511510.33091/amj.2019.170879170879Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin PathwayMarwan S. Al-Nime0Ismail I. Hussein1Yagub S. Saleh2College of Medicine, Al-Mustansiriya University, Baghdad, IraqCollege of Medicine, Al-Mustansiriya University, Baghdad, IraqDepartment of pharmacology, College of Medicine, University of Anbar, Ramadi, Anbar, IraqBackground: Pulse pressure index as a function of pulse pressure divided by systolic blood pressure served is a useful predictor of cardiovascular events. Objectives: Our aim was to assess the pulse pressure index as a discriminating variable of predicting cardiovascular events in untreated or hypertensive patients and treated with one member of angiotensin converting enzyme inhibitors or angiotensin receptor blockers by using the scores of Framingham study. Materials and methods: This observational cross-sectional study, including 140 patients who grouped into; Group I (n = 30): untreated hypertensive patients; Group II (n = 60): patients treated with angiotensin receptor blockers; and Group III (n = 50): patients treated with angiotensin converting enzyme inhibitors. Anthropometric measurements, lipid profile, and blood pressure were determined. The probability of ten-year of cardiovascular events was calculated according to the Framingham study scores using The University of Edinburgh Cardiovascular Risk Calculator (http://cvrisk.mvm.ed.ac.uk/calculator/calc.asp). Results: There is a non-significant difference between Groups and within Groups of age, smoking habit, and the values of the cardio metabolic risk factors. Pulse pressure index as an independent risk factor found to be a significant discriminator of 10-year prediction of cardiovascular events by using the receiving operating characteristic curves. Conclusion: The pulse pressure index is a useful discriminator of predicting cardiovascular events, and it will improve the Framingham prediction risk among hypertensive patients. https://amj.uoanbar.edu.iq/article_170879_ede6ed32f405035bcdd2127a19b882d9.pdfpulse pressure indexhypertensioncardiovascular indexangiotensin converting enzyme inhibitorsangiotensin receptor blockers |
| spellingShingle | Marwan S. Al-Nime Ismail I. Hussein Yagub S. Saleh Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway Al-Anbar Medical Journal pulse pressure index hypertension cardiovascular index angiotensin converting enzyme inhibitors angiotensin receptor blockers |
| title | Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway |
| title_full | Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway |
| title_fullStr | Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway |
| title_full_unstemmed | Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway |
| title_short | Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway |
| title_sort | pulse pressure index as a discriminator of predicting the cardiovascular events in hypertensive patients treated with drugs acting on angiotensinogen angiotensin pathway |
| topic | pulse pressure index hypertension cardiovascular index angiotensin converting enzyme inhibitors angiotensin receptor blockers |
| url | https://amj.uoanbar.edu.iq/article_170879_ede6ed32f405035bcdd2127a19b882d9.pdf |
| work_keys_str_mv | AT marwansalnime pulsepressureindexasadiscriminatorofpredictingthecardiovasculareventsinhypertensivepatientstreatedwithdrugsactingonangiotensinogenangiotensinpathway AT ismailihussein pulsepressureindexasadiscriminatorofpredictingthecardiovasculareventsinhypertensivepatientstreatedwithdrugsactingonangiotensinogenangiotensinpathway AT yagubssaleh pulsepressureindexasadiscriminatorofpredictingthecardiovasculareventsinhypertensivepatientstreatedwithdrugsactingonangiotensinogenangiotensinpathway |