YTHDC1-mediated microRNA maturation is essential for hematopoietic stem cells maintenance

Abstract YTHDC1, a reader of N6-methyladenosine (m6A) modifications on RNA, is posited to exert significant influence over RNA metabolism. Despite its recognized importance, the precise function and underlying mechanisms of YTHDC1 in the preservation of normal hematopoietic stem cell (HSCs) homeosta...

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Bibliographic Details
Main Authors: Hongna Zuo, Jin Liu, Bin Shen, Yue Sheng, Zhenyu Ju, Hu Wang
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02203-z
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