Investigation of a mathematical model of a bio-artificial liver using a PID-controller
The objective of this study is to develop and analyze a mathematical model of a bio-artificial liver using proportional-integral-differential a controller for managing key processes. The bio-artificial liver is a complex system that performs the fundamental functions of the liver, which is of critic...
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| Format: | Article |
| Language: | English |
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Peoples’ Friendship University of Russia (RUDN University)
2024-12-01
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| Series: | RUDN Journal of Engineering Research |
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| Online Access: | https://journals.rudn.ru/engineering-researches/article/viewFile/43093/24517 |
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| author | Alexey S. Ganshin Denis A. Andrikov |
| author_facet | Alexey S. Ganshin Denis A. Andrikov |
| author_sort | Alexey S. Ganshin |
| collection | DOAJ |
| description | The objective of this study is to develop and analyze a mathematical model of a bio-artificial liver using proportional-integral-differential a controller for managing key processes. The bio-artificial liver is a complex system that performs the fundamental functions of the liver, which is of critical importance for the development of alternative treatments for patients with liver failure. The paper describes the structure and functionality of the bio-artificial liver model, based on a review of the anatomy of the human liver, as well as on the study of bio-technological aspects of the creation of artificial organs. The application of a PID-controller is considered, which allows precise and adaptive control of processes within the model, such as the supply of nutrients and the removal of toxins. The research methodology covers the creation of a mathematical model, its computer modeling and analysis of the data obtained. The experimental part of the work is to identify the optimal parameters of the PID-controller for various operating conditions of the bio-artificial liver. The results of this study can contribute to improving the effectiveness of bio-artificial systems for supporting liver functions and offer new approaches to the implementation of artificial organs, which has significant potential for the field of transplantation and treatment of liver diseases. |
| format | Article |
| id | doaj-art-6d8d0fcfb53045559e48bb052ecdf742 |
| institution | DOAJ |
| issn | 2312-8143 2312-8151 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Peoples’ Friendship University of Russia (RUDN University) |
| record_format | Article |
| series | RUDN Journal of Engineering Research |
| spelling | doaj-art-6d8d0fcfb53045559e48bb052ecdf7422025-08-20T03:15:56ZengPeoples’ Friendship University of Russia (RUDN University)RUDN Journal of Engineering Research2312-81432312-81512024-12-0125440541210.22363/2312-8143-2024-25-4-405-41221141Investigation of a mathematical model of a bio-artificial liver using a PID-controllerAlexey S. Ganshin0https://orcid.org/0000-0003-3582-4889Denis A. Andrikov1https://orcid.org/0000-0003-0359-0897RUDN UniversityRUDN UniversityThe objective of this study is to develop and analyze a mathematical model of a bio-artificial liver using proportional-integral-differential a controller for managing key processes. The bio-artificial liver is a complex system that performs the fundamental functions of the liver, which is of critical importance for the development of alternative treatments for patients with liver failure. The paper describes the structure and functionality of the bio-artificial liver model, based on a review of the anatomy of the human liver, as well as on the study of bio-technological aspects of the creation of artificial organs. The application of a PID-controller is considered, which allows precise and adaptive control of processes within the model, such as the supply of nutrients and the removal of toxins. The research methodology covers the creation of a mathematical model, its computer modeling and analysis of the data obtained. The experimental part of the work is to identify the optimal parameters of the PID-controller for various operating conditions of the bio-artificial liver. The results of this study can contribute to improving the effectiveness of bio-artificial systems for supporting liver functions and offer new approaches to the implementation of artificial organs, which has significant potential for the field of transplantation and treatment of liver diseases.https://journals.rudn.ru/engineering-researches/article/viewFile/43093/24517proportional-integral-differential controllermodelingglucosebio-artificial liver supportdifferential equations |
| spellingShingle | Alexey S. Ganshin Denis A. Andrikov Investigation of a mathematical model of a bio-artificial liver using a PID-controller RUDN Journal of Engineering Research proportional-integral-differential controller modeling glucose bio-artificial liver support differential equations |
| title | Investigation of a mathematical model of a bio-artificial liver using a PID-controller |
| title_full | Investigation of a mathematical model of a bio-artificial liver using a PID-controller |
| title_fullStr | Investigation of a mathematical model of a bio-artificial liver using a PID-controller |
| title_full_unstemmed | Investigation of a mathematical model of a bio-artificial liver using a PID-controller |
| title_short | Investigation of a mathematical model of a bio-artificial liver using a PID-controller |
| title_sort | investigation of a mathematical model of a bio artificial liver using a pid controller |
| topic | proportional-integral-differential controller modeling glucose bio-artificial liver support differential equations |
| url | https://journals.rudn.ru/engineering-researches/article/viewFile/43093/24517 |
| work_keys_str_mv | AT alexeysganshin investigationofamathematicalmodelofabioartificialliverusingapidcontroller AT denisaandrikov investigationofamathematicalmodelofabioartificialliverusingapidcontroller |