New insights into the function and mechanisms of piRNA PMLCPIR in promoting PM2.5-induced lung cancer

New insights into the function and mechanisms of piRNA PMLCPIR in promoting PM2.5-induced lung cancer

Introduction: Extensive studies have established the correlation between long-term PM2.5 exposure and lung cancer, yet the mechanisms underlying this association remain poorly understood. PIWI-interacting RNAs (piRNAs), a novel category of small non-coding RNAs, serve important roles in various dise...

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Bibliographic Details
Main Authors: Lin Xu, Wanli Ma, Xiaoyu Huo, Jiao Luo, Ruoxi Li, Xiaoxiao Zhu, Xiangbin Kong, Kunming Zhao, Yuan Jin, Meihua Zhang, Xianshu Li, Ling Wang, Wei Han, Dianke Yu
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Advanced Research
Subjects:
PM2.5
Lung cancer
Malignant transformation
piRNA
ITGB1-PI3K-AKT axis
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224003722
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