Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding

Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding

Abstract The transition of SARS-CoV-2 into a recurrent, seasonal pathogen has underscored the need for the induction of durable immune protection. The nucleocapsid (N) protein is regarded as a promising complementary target for therapeutic and vaccine strategies, owing to its structural robustness,...

Full description

Saved in:
Bibliographic Details
Main Authors: Shaojie Xue, Suhua He, Zhaoxia Huang, Mei Yang, Guowei Hu, Xiaoxue Chen, Qiuyue Chen, Wenying Zhou, Sixiao Lin, Shoudeng Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08648-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items