Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome

Hamman-Rich syndrome, also known as acute interstitial pneumonia, is a rare and fulminant form of idiopathic interstitial lung disease. It should be considered as a cause of idiopathic acute respiratory distress syndrome. Confirmatory diagnosis requires demonstration of diffuse alveolar damage on lu...

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Main Authors: Jackrapong Bruminhent, Shahla Yassir, James Pippim
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/628743
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author Jackrapong Bruminhent
Shahla Yassir
James Pippim
author_facet Jackrapong Bruminhent
Shahla Yassir
James Pippim
author_sort Jackrapong Bruminhent
collection DOAJ
description Hamman-Rich syndrome, also known as acute interstitial pneumonia, is a rare and fulminant form of idiopathic interstitial lung disease. It should be considered as a cause of idiopathic acute respiratory distress syndrome. Confirmatory diagnosis requires demonstration of diffuse alveolar damage on lung histopathology. The main treatment is supportive care. It is not clear if glucocorticoid therapy is effective in acute interstitial pneumonia. We report the case of a 77-year-old woman without pre-existing lung disease who initially presented with mild upper respiratory tract infection and then progressed to rapid onset of hypoxic respiratory failure similar to acute respiratory distress syndrome with unknown etiology. Despite glucocorticoid therapy, she did not achieve remission and expired after 35 days of hospitalization. The diagnosis of acute interstitial pneumonia was supported by the histopathologic findings on her lung biopsy.
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spelling doaj-art-6d7260fec1914f7ea24afd525b626ced2025-08-20T02:06:43ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/628743628743Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress SyndromeJackrapong Bruminhent0Shahla Yassir1James Pippim2Department of Internal Medicine, St. Vincent's Medical Center, 2800 Main Street, Bridgeport, CT 06606, USADepartment of Internal Medicine, St. Vincent's Medical Center, 2800 Main Street, Bridgeport, CT 06606, USADepartment of Internal Medicine, St. Vincent's Medical Center, 2800 Main Street, Bridgeport, CT 06606, USAHamman-Rich syndrome, also known as acute interstitial pneumonia, is a rare and fulminant form of idiopathic interstitial lung disease. It should be considered as a cause of idiopathic acute respiratory distress syndrome. Confirmatory diagnosis requires demonstration of diffuse alveolar damage on lung histopathology. The main treatment is supportive care. It is not clear if glucocorticoid therapy is effective in acute interstitial pneumonia. We report the case of a 77-year-old woman without pre-existing lung disease who initially presented with mild upper respiratory tract infection and then progressed to rapid onset of hypoxic respiratory failure similar to acute respiratory distress syndrome with unknown etiology. Despite glucocorticoid therapy, she did not achieve remission and expired after 35 days of hospitalization. The diagnosis of acute interstitial pneumonia was supported by the histopathologic findings on her lung biopsy.http://dx.doi.org/10.1155/2011/628743
spellingShingle Jackrapong Bruminhent
Shahla Yassir
James Pippim
Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome
Case Reports in Medicine
title Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome
title_full Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome
title_fullStr Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome
title_full_unstemmed Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome
title_short Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome
title_sort acute interstitial pneumonia hamman rich syndrome as a cause of idiopathic acute respiratory distress syndrome
url http://dx.doi.org/10.1155/2011/628743
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