Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes

Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes

Abstract Background Arthropod-borne viruses (arboviruses) such as dengue virus (DENV) and Zika virus (ZIKV) pose a significant threat to global health. Novel approaches to control the spread of arboviruses focus on harnessing the antiviral immune system of their primary vector, the Aedes aegypti mos...

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Main Authors: Elodie Couderc, Anna B. Crist, Josquin Daron, Hugo Varet, Femke A. H. van Hout, Pascal Miesen, Umberto Palatini, Stéphanie Dabo, Thomas Vial, Louis Lambrechts, Sarah H. Merkling
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
Aedes aegypti
Vago
Flavivirus
Dengue virus
Vector competence
Antiviral factor
Online Access:https://doi.org/10.1186/s12915-025-02325-5
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