Association between SGLT-2 inhibitors and suicide risk in type 2 diabetes and bipolar: a real-world cohort study

Association between SGLT-2 inhibitors and suicide risk in type 2 diabetes and bipolar: a real-world cohort study

BackgroundIndividuals with bipolar disorder face a significantly elevated suicide risk, and comorbid type 2 diabetes mellitus (T2DM) further complicates their psychiatric and medical outcomes. Sodium–glucose co-transporter-2 inhibitors (SGLT-2i) have demonstrated cardiometabolic benefits in T2DM, bu...

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Bibliographic Details
Main Authors: En-Wei Chang, Jing-Yang Huang, Shih-Chang Lo, Chien-Ning Huang, Yi-Sun Yang, Edy Kornelius
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
bipolar
diabetes
SGLT2
DPP4
cohort study
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1601118/full
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