Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates

Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates

Abstract Effective suppression of gastric acid secretion promotes healing of erosive esophagitis. Treatment guidelines recommend proton pump inhibitors (PPIs) and histamine H2–receptor antagonists (H2RAs). Emerging evidence also supports potassium‐competitive acid blockers (P‐CABs). The aim was to c...

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Bibliographic Details
Main Authors: Colin W. Howden, Carmelo Scarpignato, Eckhard Leifke, Darcy J. Mulford, Gezim Lahu, Axel Facius, Yuhong Yuan, Richard Hunt
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13235
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