Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review

Mycobacterium shimoidei is a rare non-tuberculous mycobacterium (NTM) which causes pneumonia. Since its discovery in 1975, less than 50 cases have been published and this would be only the fourth case in the US. We present a case of Mycobacterium shimoidei in a 72-year-old male with symptoms of coug...

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Main Authors: Siddartha Guru, David Ingram
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S240557942500021X
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author Siddartha Guru
David Ingram
author_facet Siddartha Guru
David Ingram
author_sort Siddartha Guru
collection DOAJ
description Mycobacterium shimoidei is a rare non-tuberculous mycobacterium (NTM) which causes pneumonia. Since its discovery in 1975, less than 50 cases have been published and this would be only the fourth case in the US. We present a case of Mycobacterium shimoidei in a 72-year-old male with symptoms of cough, dyspnea, and weight loss with cavitary lung lesion on imaging. Sputum cultures grew Mycobacterium shimoidei in two separate collections, and the patient was treated with oral azithromycin, ethambutol, and rifabutin empirically. Though due to medication side effects rifabutin was stopped and other antibiotics were attempted based on susceptibilities but he was unable to tolerate any of them. Thus, only a two-drug regimen including ethambutol and azithromycin was used, on which he improved clinically and cavitary lung lesions decreased in size. In addition, we did a literature review and compiled 41 previously published cases of Mycobacterium shimoidei.
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institution Kabale University
issn 2405-5794
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publishDate 2025-08-01
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series Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
spelling doaj-art-6d69276bf5314e459bbe72fcfebe1ac22025-08-20T03:42:10ZengElsevierJournal of Clinical Tuberculosis and Other Mycobacterial Diseases2405-57942025-08-014010053010.1016/j.jctube.2025.100530Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature reviewSiddartha Guru0David Ingram1Corresponding author.; Infectious Disease, Penn State Hershey Medical Center, Hershey, PA, USAInfectious Disease, Penn State Hershey Medical Center, Hershey, PA, USAMycobacterium shimoidei is a rare non-tuberculous mycobacterium (NTM) which causes pneumonia. Since its discovery in 1975, less than 50 cases have been published and this would be only the fourth case in the US. We present a case of Mycobacterium shimoidei in a 72-year-old male with symptoms of cough, dyspnea, and weight loss with cavitary lung lesion on imaging. Sputum cultures grew Mycobacterium shimoidei in two separate collections, and the patient was treated with oral azithromycin, ethambutol, and rifabutin empirically. Though due to medication side effects rifabutin was stopped and other antibiotics were attempted based on susceptibilities but he was unable to tolerate any of them. Thus, only a two-drug regimen including ethambutol and azithromycin was used, on which he improved clinically and cavitary lung lesions decreased in size. In addition, we did a literature review and compiled 41 previously published cases of Mycobacterium shimoidei.http://www.sciencedirect.com/science/article/pii/S240557942500021XMycobacterium shimoideiCase reportNon-tuberculous mycobacterium infections
spellingShingle Siddartha Guru
David Ingram
Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Mycobacterium shimoidei
Case report
Non-tuberculous mycobacterium infections
title Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review
title_full Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review
title_fullStr Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review
title_full_unstemmed Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review
title_short Mycobacterium shimoidei cavitary pneumonia: A rare case report, literature review
title_sort mycobacterium shimoidei cavitary pneumonia a rare case report literature review
topic Mycobacterium shimoidei
Case report
Non-tuberculous mycobacterium infections
url http://www.sciencedirect.com/science/article/pii/S240557942500021X
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