Prognostic factors of the developmental outcome in neonates after hypoxic ischemic encephalopathy
Background and objective: The objectives of this study were to identify the etiologic profile and neurodevelopmental outcome of hypoxic-ischemic encephalopathy, and determine the usefulness of brain imaging to predict neurodevelopmental outcome. Method: A prospective cross-sectional hospital bas...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2022-06-01
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| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/22 |
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| Summary: | Background and objective: The objectives of this study were to identify the etiologic profile and neurodevelopmental outcome of hypoxic-ischemic encephalopathy, and determine the usefulness of brain imaging to predict neurodevelopmental outcome.
Method: A prospective cross-sectional hospital based study was done on fifty term neonates admitted in the neonatal care. All the neonates included in the study were born on term (?37 weeks of gestation) with perinatal asphyxia, admitted to the neonatal intensive care unit during the study period. All neonates included in the study underwent the first cranial ultrasonography at 6 month. Follow up of neurodevelopmental examination was done at 6 months of age, to determine the relationship between prognosis and the staging of encephalopathy with imaging methods.
Results: A total of 50 newborns enrolled in the current study with a mean APGAR ± S.D of 4.1 at the first minute and 6.5 at the fifth minute consecutively. More than half of the mothers were primigravida (64%), most of them had a normal vaginal delivery (76%) and 62% of them had prolonged labor. The majority (82%) of the babies had delayed initial crying after birth and 30% with abnormal brain ultrasonography. Half of the newborns (54%) had poor outcomes as developmental delay.
Conclusions: This study showed a significant relationship between low APGAR scores and perinatal asphyxia. This scoring system is based on clinical evaluation, brain imaging, and prognosis or neurodevelopmental delay. Most of the infants with abnormal brain ultrasonography at 6 months, had a developmental delay while those with normal brain imaging had a favorable outcome.
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| ISSN: | 2958-8979 2957-3580 |