METTL13 is essential for the survival of acute myeloid leukemia cells by regulating MYC

Abstract Recently, some methyltransferase-like (METTL) proteins have been found to play crucial roles in the development of acute myeloid leukemia (AML) through mediating RNA modifications, such as METTL3/14/16 mediated N6-methyladenosine (m6A) and METTL1 mediated N7-methylguanosine (m7G). However,...

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Main Authors: Kui Zhao, Hanyue Zhang, Shuoting Wang, Yuhang Zhou, Zhishuai Zhang, Baoqiang Kang, Huaisong Lin, Yanqi Zhang, Jiaming Gu, Carla Pantoja, Lingling Liu, Yi He, Guangjin Pan, Yongli Shan, Bing Long
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02512-x
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