The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus)
This research aimed to investigate the effect of folic acid as supportive therapy of spiramycine on weight of foetus to Toxoplasma gondii-infected pregnant mice (Mus musculus). Twenty pregnant female mice were divided into four groups as C -, C +, T1 and T2. C +, T1 and T2 were infected by Toxoplasm...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2019-12-01
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| Series: | Journal of Parasite Science |
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| Online Access: | https://e-journal.unair.ac.id/JoPS/article/view/16432 |
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| author | Alfina Azkiana Boedi Setiawan Erma Safitri Lucia Tri Suwanti Mufasirin Mufasirin Djoko Legowo |
| author_facet | Alfina Azkiana Boedi Setiawan Erma Safitri Lucia Tri Suwanti Mufasirin Mufasirin Djoko Legowo |
| author_sort | Alfina Azkiana |
| collection | DOAJ |
| description | This research aimed to investigate the effect of folic acid as supportive therapy of spiramycine on weight of foetus to Toxoplasma gondii-infected pregnant mice (Mus musculus). Twenty pregnant female mice were divided into four groups as C -, C +, T1 and T2. C +, T1 and T2 were infected by Toxoplasma gondii. C – and C + administered orally 0.5 ml aquadest, T1 administered orally 130 mg/kg BW spiramycine and 0.052 µg/g BW folic acid and T2 administered orally 0.052 µg/g BW folic acid. Experimental groups received the treatments for 5 days, then animals of each groups were sacrified. Foetuses were dissected out for observation. The weight of fetuses were measured using an analytical balance. The data weight of foetuses was presented descriptively and analyzed by ANOVA test and continued by Tukey HSD. From this study, the weight of foetuses from the pregnant mice of T1 and T2 have difference compared with the controls. The result of this research is folic acid affects the weight of foetuses to Toxoplasma gondii-infected pregnant mice. |
| format | Article |
| id | doaj-art-6d573f2883bd436091bc44a5b167d931 |
| institution | Kabale University |
| issn | 2599-0993 2656-5331 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal of Parasite Science |
| spelling | doaj-art-6d573f2883bd436091bc44a5b167d9312025-01-09T04:38:14ZengUniversitas AirlanggaJournal of Parasite Science2599-09932656-53312019-12-0131333610.20473/jops.v3i1.1643213389The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus)Alfina Azkiana0Boedi Setiawan1Erma Safitri2Lucia Tri Suwanti3Mufasirin Mufasirin4Djoko Legowo5Faculty of Veterinary Medicine, Universitas AirlanggaDepartment of Veterinary Clinic - Faculty of Veterinary Medicine, Universitas AirlanggaDepartment of Veterinary Reproduction - Faculty of Veterinary Medicine, Universitas AirlanggaDepartment of Veterinary Parasitology - Faculty of Veterinary Medicine, Universitas AirlanggaDepartment of Veterinary Parasitology - Faculty of Veterinary Medicine, Universitas AirlanggaDepartment of Veterinary Pathology - Faculty of Veterinary Medicine, Universitas AirlanggaThis research aimed to investigate the effect of folic acid as supportive therapy of spiramycine on weight of foetus to Toxoplasma gondii-infected pregnant mice (Mus musculus). Twenty pregnant female mice were divided into four groups as C -, C +, T1 and T2. C +, T1 and T2 were infected by Toxoplasma gondii. C – and C + administered orally 0.5 ml aquadest, T1 administered orally 130 mg/kg BW spiramycine and 0.052 µg/g BW folic acid and T2 administered orally 0.052 µg/g BW folic acid. Experimental groups received the treatments for 5 days, then animals of each groups were sacrified. Foetuses were dissected out for observation. The weight of fetuses were measured using an analytical balance. The data weight of foetuses was presented descriptively and analyzed by ANOVA test and continued by Tukey HSD. From this study, the weight of foetuses from the pregnant mice of T1 and T2 have difference compared with the controls. The result of this research is folic acid affects the weight of foetuses to Toxoplasma gondii-infected pregnant mice.https://e-journal.unair.ac.id/JoPS/article/view/16432folic acidtoxoplasma gondiimus musculusfoetus |
| spellingShingle | Alfina Azkiana Boedi Setiawan Erma Safitri Lucia Tri Suwanti Mufasirin Mufasirin Djoko Legowo The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus) Journal of Parasite Science folic acid toxoplasma gondii mus musculus foetus |
| title | The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus) |
| title_full | The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus) |
| title_fullStr | The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus) |
| title_full_unstemmed | The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus) |
| title_short | The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus) |
| title_sort | effect of folic acid as supportive therapy of spiramycine on weight of foetus to toxoplasma gondii infected pregnant mice mus musculus |
| topic | folic acid toxoplasma gondii mus musculus foetus |
| url | https://e-journal.unair.ac.id/JoPS/article/view/16432 |
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