LL-37 Attenuates Sepsis-Induced Lung Injury by Alleviating Inflammatory Response and Epithelial Cell Oxidative Injury via ZBP1-Mediated Autophagy

LL-37 Attenuates Sepsis-Induced Lung Injury by Alleviating Inflammatory Response and Epithelial Cell Oxidative Injury via ZBP1-Mediated Autophagy

<b>Background:</b> Sepsis-induced acute lung injury (ALI) is a serious disease constituting a heavy burden on society due to high mortality and morbidity. Inflammation and oxidative stress constitute key pathological mechanisms in ALI caused by sepsis. LL-37 can improve the survival of s...

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Bibliographic Details
Main Authors: Hu Gao, Fajuan Tang, Bin Chen, Xihong Li
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxins
Subjects:
sepsis-induced ALI
LL-37
oxidative injury
inflammation
autophagy
Online Access:https://www.mdpi.com/2072-6651/17/6/306
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