Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period

The study aimed to investigate the effect of in ovo (IO) leptin injection on yolk sac leptin concentration, embryo development, blood lipid metabolism, and biochemical parameters of broiler chicks during the early post-hatching period. Hatching eggs were weighed and placed in an incubator with 100 e...

Full description

Saved in:
Bibliographic Details
Main Authors: Bülent CELLAK, Elif BABACANOĞLU
Format: Article
Language:English
Published: Yuzuncu Yil University Faculty of Agriculture 2022-06-01
Series:Yüzüncü Yıl Üniversitesi Tarim Bilimleri Dergisi
Subjects:
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849701012580859904
author Bülent CELLAK
Elif BABACANOĞLU
author_facet Bülent CELLAK
Elif BABACANOĞLU
author_sort Bülent CELLAK
collection DOAJ
description The study aimed to investigate the effect of in ovo (IO) leptin injection on yolk sac leptin concentration, embryo development, blood lipid metabolism, and biochemical parameters of broiler chicks during the early post-hatching period. Hatching eggs were weighed and placed in an incubator with 100 eggs/4 replications/group. The groups were: non-injected group (C); and 3 injected groups with 100 μl of phosphate buffer solution (PBS); 0.5 μl leptin (L0.5), and 1 μl leptin (L1) in 100 μl of PBS. Pure leptin hormone dissolved in PBS was injected into the yolk sac on day 7 of incubation. Yolk/yolk sac leptin concentrations at the onset of incubation, on days 7 and 15 of incubation, and at hatching were determined. Embryo/chick development was determined at all ages. Serum leptin, tri-iodothyronine (T3), thyroxine (T4), creatine kinase, total protein, uric acid, and lipid profiles were measured at hatching and day 7 of chick age. The leptin level of the yolk was similar to the leptin level of the yolk sac at hatching. Leptin level of a yolk sac was higher on 7th day than at other ages. IO injection* age was significant for serum leptin level, which was similar to one-day chicks in the L0.5 at day 7 of chick age. T3, T4, creatine kinase, uric acid, lipid profiles, and embryo/chick development did not change with IO leptin. Serum HDL level was higher in the leptin groups than C and PBS groups at hatching. IO leptin application affects blood lipid metabolism depending on dose level for male broiler chicks at the early post-hatch period, without affecting embryo/chick development.
format Article
id doaj-art-6d500ec621014a089ac67f75c3bc2245
institution DOAJ
issn 1308-7576
1308-7584
language English
publishDate 2022-06-01
publisher Yuzuncu Yil University Faculty of Agriculture
record_format Article
series Yüzüncü Yıl Üniversitesi Tarim Bilimleri Dergisi
spelling doaj-art-6d500ec621014a089ac67f75c3bc22452025-08-20T03:18:05ZengYuzuncu Yil University Faculty of AgricultureYüzüncü Yıl Üniversitesi Tarim Bilimleri Dergisi1308-75761308-75842022-06-0132233935010.29133/yyutbd.1089888Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period Bülent CELLAKhttps://orcid.org/0000-0002-0936-9141Elif BABACANOĞLUhttps://orcid.org/0000-0002-6329-315XThe study aimed to investigate the effect of in ovo (IO) leptin injection on yolk sac leptin concentration, embryo development, blood lipid metabolism, and biochemical parameters of broiler chicks during the early post-hatching period. Hatching eggs were weighed and placed in an incubator with 100 eggs/4 replications/group. The groups were: non-injected group (C); and 3 injected groups with 100 μl of phosphate buffer solution (PBS); 0.5 μl leptin (L0.5), and 1 μl leptin (L1) in 100 μl of PBS. Pure leptin hormone dissolved in PBS was injected into the yolk sac on day 7 of incubation. Yolk/yolk sac leptin concentrations at the onset of incubation, on days 7 and 15 of incubation, and at hatching were determined. Embryo/chick development was determined at all ages. Serum leptin, tri-iodothyronine (T3), thyroxine (T4), creatine kinase, total protein, uric acid, and lipid profiles were measured at hatching and day 7 of chick age. The leptin level of the yolk was similar to the leptin level of the yolk sac at hatching. Leptin level of a yolk sac was higher on 7th day than at other ages. IO injection* age was significant for serum leptin level, which was similar to one-day chicks in the L0.5 at day 7 of chick age. T3, T4, creatine kinase, uric acid, lipid profiles, and embryo/chick development did not change with IO leptin. Serum HDL level was higher in the leptin groups than C and PBS groups at hatching. IO leptin application affects blood lipid metabolism depending on dose level for male broiler chicks at the early post-hatch period, without affecting embryo/chick development.broilerembryo developmentin ovoleptinyolk sac
spellingShingle Bülent CELLAK
Elif BABACANOĞLU
Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period
Yüzüncü Yıl Üniversitesi Tarim Bilimleri Dergisi
broiler
embryo development
in ovo
leptin
yolk sac
title Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period
title_full Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period
title_fullStr Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period
title_full_unstemmed Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period
title_short Influence of In Ovo Leptin Injection into Yolk Sac on Embryo Development, Blood Biochemical Parameters and Lipid Metabolism of Broiler Chicks during Early Post-Hatching Period
title_sort influence of in ovo leptin injection into yolk sac on embryo development blood biochemical parameters and lipid metabolism of broiler chicks during early post hatching period
topic broiler
embryo development
in ovo
leptin
yolk sac
work_keys_str_mv AT bulentcellak influenceofinovoleptininjectionintoyolksaconembryodevelopmentbloodbiochemicalparametersandlipidmetabolismofbroilerchicksduringearlyposthatchingperiod
AT elifbabacanoglu influenceofinovoleptininjectionintoyolksaconembryodevelopmentbloodbiochemicalparametersandlipidmetabolismofbroilerchicksduringearlyposthatchingperiod