Eccrine Spiradenoma Arising from the Breast Skin
Eccrine spiradenomas are uncommon, benign lesions, which are thought to originate from the eccrine sweat glands. They are common in young adults and are without a sex predilection. Here we report a case of eccrine spiradenoma of the breast skin in a 39-year-old woman who presented with a breast nodu...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2015/615158 |
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| author | Mark A. Benedict Ugur Ozerdem |
| author_facet | Mark A. Benedict Ugur Ozerdem |
| author_sort | Mark A. Benedict |
| collection | DOAJ |
| description | Eccrine spiradenomas are uncommon, benign lesions, which are thought to originate from the eccrine sweat glands. They are common in young adults and are without a sex predilection. Here we report a case of eccrine spiradenoma of the breast skin in a 39-year-old woman who presented with a breast nodule for 10 years. It is crucial to take eccrine spiradenoma into consideration in superficial, well-circumscribed, breast skin/subcutaneous lesions. It is useful to recognize the two-cell populations constituting this tumor: small, dark, basaloid cells with hyperchromatic nuclei, which are immunoreactive for P63 and calponin, and larger cells with a pale nucleus, often near the center of the cluster (inner cells), which are immunoreactive for CK7 and CD117 (C-kit). |
| format | Article |
| id | doaj-art-6d3efb211a8f42f8b556f33ebce05081 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-6d3efb211a8f42f8b556f33ebce050812025-02-03T05:47:18ZengWileyCase Reports in Pathology2090-67812090-679X2015-01-01201510.1155/2015/615158615158Eccrine Spiradenoma Arising from the Breast SkinMark A. Benedict0Ugur Ozerdem1Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USADepartment of Pathology, Yale University School of Medicine, New Haven, CT 06520, USAEccrine spiradenomas are uncommon, benign lesions, which are thought to originate from the eccrine sweat glands. They are common in young adults and are without a sex predilection. Here we report a case of eccrine spiradenoma of the breast skin in a 39-year-old woman who presented with a breast nodule for 10 years. It is crucial to take eccrine spiradenoma into consideration in superficial, well-circumscribed, breast skin/subcutaneous lesions. It is useful to recognize the two-cell populations constituting this tumor: small, dark, basaloid cells with hyperchromatic nuclei, which are immunoreactive for P63 and calponin, and larger cells with a pale nucleus, often near the center of the cluster (inner cells), which are immunoreactive for CK7 and CD117 (C-kit).http://dx.doi.org/10.1155/2015/615158 |
| spellingShingle | Mark A. Benedict Ugur Ozerdem Eccrine Spiradenoma Arising from the Breast Skin Case Reports in Pathology |
| title | Eccrine Spiradenoma Arising from the Breast Skin |
| title_full | Eccrine Spiradenoma Arising from the Breast Skin |
| title_fullStr | Eccrine Spiradenoma Arising from the Breast Skin |
| title_full_unstemmed | Eccrine Spiradenoma Arising from the Breast Skin |
| title_short | Eccrine Spiradenoma Arising from the Breast Skin |
| title_sort | eccrine spiradenoma arising from the breast skin |
| url | http://dx.doi.org/10.1155/2015/615158 |
| work_keys_str_mv | AT markabenedict eccrinespiradenomaarisingfromthebreastskin AT ugurozerdem eccrinespiradenomaarisingfromthebreastskin |