Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines
Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which rais...
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2025-08-01
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| Series: | ChemistryOpen |
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| Online Access: | https://doi.org/10.1002/open.202400470 |
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| author | Mohammad Qandalee Aliyeh Khajeh‐Khezri Mohammad Alikarami Silvia Izquierdo Ignacio M. López‐Coca |
| author_facet | Mohammad Qandalee Aliyeh Khajeh‐Khezri Mohammad Alikarami Silvia Izquierdo Ignacio M. López‐Coca |
| author_sort | Mohammad Qandalee |
| collection | DOAJ |
| description | Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which raise environmental and health concerns while requiring high energy inputs. This study addresses these challenges by applying the principles of green chemistry to develop a sustainable, efficient, and environmentally friendly synthetic route for aryl quinolines. |
| format | Article |
| id | doaj-art-6d3eed3dc57342b8a3cc577b5b6c3992 |
| institution | Kabale University |
| issn | 2191-1363 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | ChemistryOpen |
| spelling | doaj-art-6d3eed3dc57342b8a3cc577b5b6c39922025-08-21T12:05:32ZengWiley-VCHChemistryOpen2191-13632025-08-01148n/an/a10.1002/open.202400470Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl QuinolinesMohammad Qandalee0Aliyeh Khajeh‐Khezri1Mohammad Alikarami2Silvia Izquierdo3Ignacio M. López‐Coca4Department of Basic Sciences Garmsar Branch Islamic Azad University Garmsar 3581631167 IranDepartment of Chemistry Tarbiat Modares University Tehran 14115111 IranDepartment of Chemistry Ilam Branch Islamic Azad University Ilam 6931133145 IranDepartment of Organic and Inorganic Chemistry School of Technology INTERRA Universidad de Extremadura Cáceres 10003 SpainDepartment of Organic and Inorganic Chemistry School of Technology INTERRA Universidad de Extremadura Cáceres 10003 SpainHeterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which raise environmental and health concerns while requiring high energy inputs. This study addresses these challenges by applying the principles of green chemistry to develop a sustainable, efficient, and environmentally friendly synthetic route for aryl quinolines.https://doi.org/10.1002/open.202400470arylquinolinescatalyst‐free reactionsheterocyclesorganic electronic devices |
| spellingShingle | Mohammad Qandalee Aliyeh Khajeh‐Khezri Mohammad Alikarami Silvia Izquierdo Ignacio M. López‐Coca Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines ChemistryOpen arylquinolines catalyst‐free reactions heterocycles organic electronic devices |
| title | Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines |
| title_full | Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines |
| title_fullStr | Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines |
| title_full_unstemmed | Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines |
| title_short | Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines |
| title_sort | exploring a water ethyl acetate system for the efficient synthesis of 4 aryl quinolines |
| topic | arylquinolines catalyst‐free reactions heterocycles organic electronic devices |
| url | https://doi.org/10.1002/open.202400470 |
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