snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation

snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation

IntroductionCold stimulation induces browning of subcutaneous white adipose tissue (sWAT), making it a prime target for treating obesity and metabolic disorders. However, this remodeling is reversible: upon return to thermoneutrality (rewarming), sWAT whitens and loses its enhanced metabolic functio...

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Bibliographic Details
Main Authors:	Yusha Yang, Guanyu Zhang, Ting Yi, Shuran Yang, Shuai Wu, Yongqiang Zhang, Li Zhang, Xi Li, Xiuxuan Wu, Jun Li, Danfeng Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	single-nucleus RNA sequencing thermoneutrality subcutaneous white adipose tissue plasticity cold stimulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1578180/full
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