Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts

Gold nanoparticles have been used as drug carriers and imaging reagents. The plant extract-capped gold nanoparticles provide better properties than chemically synthesized gold nanoparticles. In this study, Zingiber zerumbet extract-mediated green production of gold nanoparticles (Z. zerumbet@Au NPs)...

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Main Authors: Wayne C. Liao, Collin S. Liao, Yu-Chen Lin, Ching-Yi Lien
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2024/1358495
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author Wayne C. Liao
Collin S. Liao
Yu-Chen Lin
Ching-Yi Lien
author_facet Wayne C. Liao
Collin S. Liao
Yu-Chen Lin
Ching-Yi Lien
author_sort Wayne C. Liao
collection DOAJ
description Gold nanoparticles have been used as drug carriers and imaging reagents. The plant extract-capped gold nanoparticles provide better properties than chemically synthesized gold nanoparticles. In this study, Zingiber zerumbet extract-mediated green production of gold nanoparticles (Z. zerumbet@Au NPs) was established. Based on the UV-visible spectroscopy and transmission electron microscope (TEM) results, most Z. zerumbet@Au NPs were spherical. When more Z. zerumbet extracts were added, more spherical nanoparticles were formed. The hydrodynamic size changed slightly along with time, and the average size was approximately 170 nm. Capping of Z. zerumbet extract on the surface of gold nanoparticles was confirmed by Fourier transform infrared spectroscopy (FTIR). In general, phenolic compounds or flavonoid compounds were considered to be the reducing agent. However, zerumbone was identified as the reducing agent in this study. The resulting oxidized products were characterized by high-performance liquid chromatography-mass spectrometry (HPLC-MS). As a result, the solvent was proven to be involved in nanoparticle synthesis. Overall, Z zerumbet@Au NPs showed great potential to be used in cosmetic- or biomedicine-related fields.
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spelling doaj-art-6d3608468ed14bfaab34dd0488352d5e2025-08-20T03:33:52ZengWileyJournal of Chemistry2090-90712024-01-01202410.1155/2024/1358495Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet ExtractsWayne C. Liao0Collin S. Liao1Yu-Chen Lin2Ching-Yi Lien3Department of NursingDepartment of Biotechnology and Bioindustry SciencesDepartment of Applied ChemistryDepartment of Applied ChemistryGold nanoparticles have been used as drug carriers and imaging reagents. The plant extract-capped gold nanoparticles provide better properties than chemically synthesized gold nanoparticles. In this study, Zingiber zerumbet extract-mediated green production of gold nanoparticles (Z. zerumbet@Au NPs) was established. Based on the UV-visible spectroscopy and transmission electron microscope (TEM) results, most Z. zerumbet@Au NPs were spherical. When more Z. zerumbet extracts were added, more spherical nanoparticles were formed. The hydrodynamic size changed slightly along with time, and the average size was approximately 170 nm. Capping of Z. zerumbet extract on the surface of gold nanoparticles was confirmed by Fourier transform infrared spectroscopy (FTIR). In general, phenolic compounds or flavonoid compounds were considered to be the reducing agent. However, zerumbone was identified as the reducing agent in this study. The resulting oxidized products were characterized by high-performance liquid chromatography-mass spectrometry (HPLC-MS). As a result, the solvent was proven to be involved in nanoparticle synthesis. Overall, Z zerumbet@Au NPs showed great potential to be used in cosmetic- or biomedicine-related fields.http://dx.doi.org/10.1155/2024/1358495
spellingShingle Wayne C. Liao
Collin S. Liao
Yu-Chen Lin
Ching-Yi Lien
Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts
Journal of Chemistry
title Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts
title_full Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts
title_fullStr Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts
title_full_unstemmed Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts
title_short Characterization of Gold Nanoparticles Synthesized with Zingiber zerumbet Extracts
title_sort characterization of gold nanoparticles synthesized with zingiber zerumbet extracts
url http://dx.doi.org/10.1155/2024/1358495
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AT yuchenlin characterizationofgoldnanoparticlessynthesizedwithzingiberzerumbetextracts
AT chingyilien characterizationofgoldnanoparticlessynthesizedwithzingiberzerumbetextracts