Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature

Pregnancy coexisting with the diagnosis of malignancy is rare. It poses a major management dilemma to the oncologist where adequate oncology outcomes need to be weighed against the fetal well-being. Use of chemotherapy during pregnancy is determined by the type of malignancy, stage, gestational age,...

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Main Authors: Nidhi Gupta, Rakshit Manali Manosij, Kislay Dimri, Awadhesh Kumar Pandey, Irwinjit Kaur, Poonam Goel
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd.
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1809379
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author Nidhi Gupta
Rakshit Manali Manosij
Kislay Dimri
Awadhesh Kumar Pandey
Irwinjit Kaur
Poonam Goel
author_facet Nidhi Gupta
Rakshit Manali Manosij
Kislay Dimri
Awadhesh Kumar Pandey
Irwinjit Kaur
Poonam Goel
author_sort Nidhi Gupta
collection DOAJ
description Pregnancy coexisting with the diagnosis of malignancy is rare. It poses a major management dilemma to the oncologist where adequate oncology outcomes need to be weighed against the fetal well-being. Use of chemotherapy during pregnancy is determined by the type of malignancy, stage, gestational age, chemotherapy agent, and the risk of placental transfer.
format Article
id doaj-art-6d3113ccfb9f4e258984f1025945bf6e
institution Kabale University
issn 0971-5851
0975-2129
language English
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-6d3113ccfb9f4e258984f1025945bf6e2025-08-20T03:44:50ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-212910.1055/s-0045-1809379Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of LiteratureNidhi Gupta0https://orcid.org/0000-0003-4079-2631Rakshit Manali Manosij1Kislay Dimri2Awadhesh Kumar Pandey3Irwinjit Kaur4Poonam Goel5Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, IndiaDepartment of Radiation Oncology, Government Medical College and Hospital, Chandigarh, IndiaDepartment of Radiation Oncology, Government Medical College and Hospital, Chandigarh, IndiaDepartment of Radiation Oncology, Government Medical College and Hospital, Chandigarh, IndiaDepartment of Radiodiagnosis, Government Medical College and Hospital, Chandigarh, IndiaDepartment of Obstetrics and Gynaecology, Government Medical College and Hospital, Chandigarh, IndiaPregnancy coexisting with the diagnosis of malignancy is rare. It poses a major management dilemma to the oncologist where adequate oncology outcomes need to be weighed against the fetal well-being. Use of chemotherapy during pregnancy is determined by the type of malignancy, stage, gestational age, chemotherapy agent, and the risk of placental transfer.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1809379pregnancychemotherapyfetal malformationsteratogeniccorpus-callosum agenesisskeletal dysplasiacase report
spellingShingle Nidhi Gupta
Rakshit Manali Manosij
Kislay Dimri
Awadhesh Kumar Pandey
Irwinjit Kaur
Poonam Goel
Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature
Indian Journal of Medical and Paediatric Oncology
pregnancy
chemotherapy
fetal malformations
teratogenic
corpus-callosum agenesis
skeletal dysplasia
case report
title Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature
title_full Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature
title_fullStr Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature
title_full_unstemmed Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature
title_short Chemotherapy during First Trimester Pregnancy Leading to Fetal Malformation: A Case Report with Review of Literature
title_sort chemotherapy during first trimester pregnancy leading to fetal malformation a case report with review of literature
topic pregnancy
chemotherapy
fetal malformations
teratogenic
corpus-callosum agenesis
skeletal dysplasia
case report
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1809379
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AT kislaydimri chemotherapyduringfirsttrimesterpregnancyleadingtofetalmalformationacasereportwithreviewofliterature
AT awadheshkumarpandey chemotherapyduringfirsttrimesterpregnancyleadingtofetalmalformationacasereportwithreviewofliterature
AT irwinjitkaur chemotherapyduringfirsttrimesterpregnancyleadingtofetalmalformationacasereportwithreviewofliterature
AT poonamgoel chemotherapyduringfirsttrimesterpregnancyleadingtofetalmalformationacasereportwithreviewofliterature